Neurological and systemic complications of tuberculous meningitis and its treatment at Auckland City Hospital, New Zealand

Undernutrition as Risk Factor of Hydrocephalus Prevalence in Children with Tuberculous Meningitis

“…These results were in contrast to the study reported by Raut et al 5 in which these three variables are the predictors of hydrocephalus. Moreover, this study was in line with the study of Anderson et al 3 which found seizure and motoric paralysis only occurred in 28% and 5% of subjects and were not statistically significant. In this study and a study of Anderson et al 3 , motoric paralysis and history of seizure were assessed from hospital medical records.…”

“…Moreover, this study was in line with the study of Anderson et al 3 which found seizure and motoric paralysis only occurred in 28% and 5% of subjects and were not statistically significant. In this study and a study of Anderson et al 3 , motoric paralysis and history of seizure were assessed from hospital medical records. Information on medical records can be erroneously recorded resulting in information bias.…”

“…A study reported that the most often neurological complication is hydrocephalus (42%). 3 Tuberculous meningitis patients with hydrocephalus after ventriculoperitoneal shunt has poor outcome: 42.1% died while the rest ranging from good outcome to moderate disability. 4 Rautet et al 5 reported that predictor factors of hydrocephalus are advanced stage of disease, severe disability, duration of disease >2 months, seizures, impaired vision, papilledema, cranial nerve palsy (N VI), hemiparesis, cerebrospinal fluid total cell count >100/mm 3 , cerebrospinal fluid protein >2.5 g/L.…”

“…In addition, weak immunity supports exudate formation in basilar area. 3 This study was conducted to identify the impact of undernutrition to the insidence of hydrocephalus in children with tuberculous meningitis.…”

Seizure increases electroencephalographic abnormalities in children with tuberculous meningitis

“…(1) The most common complications of TBM observed in 81 long-term survivors were epilepsy (11%) and cognitive impairment (12%). (5) Seizures are a common clinical feature of TBM, occurring at any stage of the infection. They cause an additional burden of disability, producing neurological deficits which are a significant predictor of mortality, often requiring long-term antiepileptic therapy.…”