Neurologic treatment strategies in autism: An overview of medical intervention strategies

Characteristics and Dental Experiences of Autistic Children in Saudi Arabia: Cross-sectional Study

“…It has been reported that, these drugs have no effect on the person's ability to socialize or communicate but are effective in controlling some of the associated symptoms of the disorder: hyperactivity (for example, methylphenidate), repetitive behaviors (for example, fluoxetine and sertraline) and for aggressive behaviors (for example, carbamazepine, valproate, risperidone and olanzapine) (Lindsay and Aman 2003;Aman 2004;Palermo and Curatolo 2004;Chez et al 2004).…”

Risperidone Improves Behavioral Symptoms in Children with Autism in a Randomized, Double-Blind, Placebo-Controlled Trial

“…However, when persistent maladaptive behaviors inhibit therapeutic progress, pharmacological therapy may be considered as a treatment option. Pharmacological therapy focuses on targeting problem behaviors and treating with a symptom-based approach (Chez, Memon, & Hung, 2004). Numerous studies have evaluated a variety of medications for reducing different behavioral problems in subjects with PDD (Posey & McDougle, 2000).…”

“…Hyperactivity and attention disorders in children with PDD have been targeted by psychostimulants (e.g., methylphenidate), atypical antipsychotics (e.g., risperidone, olanzapine), and alpha agonists (e.g., guanfacine, clonidine) (Aman, 2004). Aggressive or self-injurious behavior has been predominantly targeted by both typical and atypical antipsychotic medications (e.g., haloperidol, risperidone) (Chez et al, 2004). For many of these compounds, controlled, large-scale, long-term studies are not available, making it difficult to reach concrete conclusions on their efficacy and tolerability in treating PDD.…”

Effectiveness of Medication Combined with Intensive Behavioral Intervention for Reducing Aggression in Youth with Autism Spectrum Disorder

“…There are a large number of treatment options available for reducing aggression in children with autism, but many have little to no evidence base (Goin-Kochel et al 2007). Growing evidence supports the use of intensive behavioral intervention (IBI) (Matson et al 1996;Howlin et al 2009) or medications (McDougle 2002Chez et al 2004;Malone et al 2005) to treat difficult behavior in children with ASD. To the authors' knowledge, no studies have examined the simultaneous application of these treatments toward reducing aggression in youths with autism.…”