Neurologic Complications of Genitourinary Malignancies

Schiff, David; Trump, Donald L.; Wen, Patrick Y.

doi:10.1007/978-1-59259-317-0_22

Cited by 3 publications

(2 citation statements)

References 113 publications

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“…Penyebab edema pada tumor otak biasanya edema vasogenik, sehingga diberikan deksametason dosis tinggi intravena untuk antiinflamasi dan memperbaiki integritas sawar darah otak. [6] Hal ini terbukti dengan perbaikan kesadaran setelah pemberian deksametason.…”

Section: Pembahasanunclassified

Ekstensi Dan Invasi Intrakranial Tumor Kulit Kepala: Tantangan Diagnosis Dan Tatalaksana

Yolanda¹,

Aninditha²,

Sofyan³

et al. 2023

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Tumor di kulit kepala sangat jarang, hanya 1-2% yang bersifat ganas serta memiliki kecenderungan untuk ekstensi dan invasi ke intrakranial. Ekstensi ini dapat menyebabkan berbagai komplikasi neurologis, seperti nyeri kanker, peningkatan tekanan intrakranial (TIK), dan defisit neurologis lain. Seorang perempuan, 37 tahun, datang dengan penurunan kesadaran sejak 2 hari sebelumnya. Pasien memiliki riwayat benjolan di puncak kepala sejak 4 tahun, berulang 3 kali pascareseksi tanpa pengobatan spesifik sebelumnya. Pada rekurensi ketiga tumor membesar hingga terlihat ada bagian yang masuk ke dalam tempurung kepala yang terasa nyeri. Nyeri memberat di seluruh kepala disertai gangguan lapang pandang kuadranopia homonim inferior dekstra, paresis nervus VII dekstra sentral, dan hemiparesis dekstra. CT scan kepala kontras didapatkan lesi heterogen berlobulasi di regio parietooksipital, meluas ekstraaksial dan ke intraserebral, disertai edema vasogenik dengan destruksi os parietal dan oksipital. Hasil patologi anatomi berupa trichilemmal carcinoma. Pasien mendapatkan terapi morfin drip 10mg/24jam yang kemudian diganti dengan patch dosis ekuivalennya, deksametason 2x10mg IV tapering off bertahap sesuai kondisi klinis, gabapentin 2x300mg, serta wholebrain radiotherapy (WBRT) 30 Gy sebanyak 10 kali. Nyeri teratasi menjadi nyeri ringan saat pasien pulang dan dalam keadaan sadar. Kata kunci: invasi intrakranial, nyeri kanker, peningkatan tekanan intrakranial, tumor kulit kepala

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Section: Pembahasanunclassified

Ekstensi Dan Invasi Intrakranial Tumor Kulit Kepala: Tantangan Diagnosis Dan Tatalaksana

Yolanda¹,

Aninditha²,

Sofyan³

et al. 2023

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“…20-40% of cancer patients have brain metastases, which are 10:1 more common than the original brain tumour 6. Patients with metastatic brain tumours are estimated to be 98,000 to 170,000 annually in the United States 11. In anatomical pathology, the frequency of metastasis to the brain from lung cancer with a ratio of NSCLC is 36% and SCLC is 56%.…”

mentioning

confidence: 99%

Characteristics of Lung Cancer Patients with Brain Metastases based on Baseline Head Computerized Tomography (CT)-scan in Arifin Achmad Hospital October 2022 - June 2023

Sari,

Fauzi,

Simanjuntak

2024

Respir Scie

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Background: The majority of lung cancer cases are often discovered at a late stage because it frequently develops without symptoms in the early stages. Many lung cancer deaths are caused by metastases to other organs. The purpose of this study was to examine the features of lung cancer patients with brain metastases using baseline CT scan data. Method: Between October 2022 and June 2023, a cross-sectional study was conducted at the Arifin Achmad Hospital in Pekanbaru on all newly diagnosed lung cancer patients with brain metastases who also met the inclusion and exclusion criteria. Results: Eight subjects of lung cancer with brain metastasis were found from 49 patients. All subjects were male with age mostly in between 40 and 60 years. Three subjects (37.5%) were Squamous Cell Carcinoma (SCC), four subject (50%) were adenocarcinoma and 1 (12.5%) were SCLC. Conclusion: This study discovered that 16.3% of patients who met the inclusion criteria had lung cancer with brain metastases. Further research should be done on a cohort study and a preventive strategy for lung cancer with brain metastases.

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