Neuroleptic malignant syndrome induced acute renal failure: Is mental retardation an additional risk factor?

Abstract

Neuroleptic malignant syndrome is a rare but serious complication of neuroleptic treatment. It is a disorder which is usually characterized by muscle contraction and changes in consciousness, extrapyramidal symptoms, hyperpyrexia and blood pressure irregularities that often depend on the use of conventional antipsychotic drugs. In this case report, we discuss acute renal failure induced by neuroleptic malignant syndrome developing on the basis of chronic kidney disease in a patient with mental retardation.