Neuroleptic malignant syndrome associated with metoclopramide.

Robinson, Michael; Kennett, Roger H.; Harding, A E; Legg, N. J.; Clarke, B.R.

doi:10.1136/jnnp.48.12.1304

Cited by 33 publications

(11 citation statements)

References 5 publications

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“…Clinical exam¬ ination disclosed the following values: blood pressure (BP), 135/90 mm Hg; pulse rate, 60 beats per minute; respiratory rate, 16 breaths per minute; and oral temperature, 36.9°C (98.4°F). The patient's face was pasty, with slight periorbital edema, and his skin was dry and scaly.…”

Section: Report Of a Casementioning

confidence: 99%

“…To our knowledge, there is only one English-language report of metoclo¬ pramide-induced NMS. 16 We describe two additional pa¬ tients recently seen at our institution who developed NMS in association with metoclopramide therapy. REPORT hydrochloride therapy (20 mg every six hours) was begun during the June hospitalization, and the patient's symptoms resolved over the ensuing 24 to 36 hours.…”

mentioning

confidence: 99%

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Metoclopramide-Induced Neuroleptic Malignant Syndrome

Friedman¹,

Weinrauch²,

D’Elia³

1987

Arch Intern Med

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Section: Report Of a Casementioning

confidence: 99%

mentioning

confidence: 99%

Metoclopramide-Induced Neuroleptic Malignant Syndrome

Friedman¹,

Weinrauch²,

D’Elia³

1987

Arch Intern Med

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“…This includes not only neuroleptics in a narrow sense (either typical or atypical antipsychotics) prescribed for the control of psychotic symptoms, but also several classes of drugs with the potential to block D 2 receptors in CNS used as antidepressants, antiemetics, anesthetics, and sedatives (e.g., Robinson et al, 1985;L.S. Friedman et al, 1987;Taylor & Schwartz, 1988;Madakasira, 1989;Spirt et al, 1992;Chan-Tack, 1999).…”

Section: Precipitating Agentsmentioning

confidence: 99%

Encephalopathy Associated with Psychotropic Drug Therapy

Odagaki¹

2012

Miscellanea on Encephalopathies - A Second Look

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“…NMS has been found to be associated with antipsychotics, and there are few published reports related to metoclopramide use [2,3]. Earlier studies and case reports list the mortality of NMS to be around 20-30% [2,4], yet Shalev et al [5] showed that mortality from NMS has significantly reduced to 11.5%.…”

mentioning

confidence: 99%

“…Earlier studies and case reports list the mortality of NMS to be around 20-30% [2,4], yet Shalev et al [5] showed that mortality from NMS has significantly reduced to 11.5%. Furthermore, predictors of mortality are organic brain syndrome, comatose presentation, age older than 65 years, and temperature greater than 40°C [6].…”

mentioning

confidence: 99%