Neuroinflammation preceding primary central nervous system lymphoma (PCNSL) – Case reports and literature review

Primary central nervous system lymphoma: A mirror type presentation in an immunocompetent patient

“…[ 31 ] It is attributed to being initially inflammatory and demyelinating lesions. [ 21 , 26 ] It occurs mainly in the immunocompromised population, and within the immunocompetent population, those>60 years are the most affected,[ 22 , 23 ] with similar clinical manifestations as in young patients. This case had an atypical presentation, correlating the clinical data with the imaging studies: an immunocompetent elderly patient without EBV or CMV infection.…”

Correlation of functional magnetic resonance imaging features of primary central nervous system lymphoma with vasculogenic mimicry and reticular fibers

“…It has been suggested that there is a close relationship between the aggressiveness of PCNSL and VM [ 9 ]. In addition, PCNSL lesions are also rich in reticular fibers, which infiltrate a large number of tumor cells, and it is believed that tumor lesions with reticular fibrous structure are highly aggressive and have a higher metastasis rate [ 10 ]. In previous studies, some scholars believe that reticular fibers are the body's defense against tumors, and there are only a small number of sparse reticular fibers or no reticular fibers around the tumor cancer nest with good differentiation and low malignancy, while rich and dense reticular fibers can be seen around the poorly differentiated and aggressive tumor cancer nest [ 11 ].…”