Neuroimmunomodulation with enkephalins: Enhancement of human natural killer (NK) cell activity in vitro

Faith, Robert E.; Liang, Huey J.; Murgo, Anthony J.; Plotnikoff, Nicholas P.

doi:10.1016/0090-1229(84)90093-x

Cited by 134 publications

(33 citation statements)

References 24 publications

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“…MATHEWS et al (1983) found met-enkephalin to stimulate natural killer cell tumoricidal activity in vitro at nM concentrations, and other groups have reported similar findings (FAITH et al 1984). Met-enkephalin also stimulated natural killer cell activity in mice following systemic injection at doses of 0.5 mg/ animal (FAITH and MURGO 1988).…”

Section: Enkephalinmentioning

confidence: 85%

Opioids in Immunologic Processes

Bryant¹,

Holaday²

1993

Opioids II

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Section: Enkephalinmentioning

confidence: 85%

Opioids in Immunologic Processes

Bryant¹,

Holaday²

1993

Opioids II

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“…β-Casomorphin-7 derived from β-casein was used as a possible immunostimulating substrate, since it is a ligand of opioid receptors that have also been found on the surface of human T-lymphocytes (33)(34)(35).…”

Section: Immunomodulatory Peptidesmentioning

confidence: 99%

Cheese as Functional Food: The Example of Parmigiano Reggiano and Grana Padano

Summer

Formaggioni

Franceschi

et al. 2017

Food Technol. Biotechnol.

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SummaryItalian hard cooked types of cheese, like Parmigiano Reggiano and Grana Padano, are characterised by positive nutritional qualities. In fact, they contain substances that have particular biological activities, and therefore they can be fully considered, according to the defi nition given by the European Unit, as 'functional' foods. This short review concisely describes these components and the benefi cial eff ects related to their activities. The description of the biologically active components has been organised in the following paragraphs: protein and peptides, fat and lipids, carbohydrates and prebiotics, probiotic bacteria, vitamins, mineral salts, and components of dairy products active in disease prevention. In particular, several known bioactive peptides were found in Parmigiano Reggiano cheese samples: for example, phosphopeptides, which are known for their mineral-binding capacity and vehiculation activity, peptides with immunomodulatory activity, and angiotensin-converting enzyme-inhibitory peptides with anti-hypertensive eff ects. Among lipids, the role of conjugated linoleic acid and other fatt y acids present in these cheese types was taken into consideration. The presence of oligosaccharides with prebiotic properties and probiotic bacteria was also described. Finally, particular emphasis was given to highly available calcium and its impact on bone health.

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“…For example, gamma-interferon production has been shown to be influenced by opioid peptides (1), and NK activity appears to be enhanced by both beta-endorphin (2,3) and metenkephalin (4)(5)(6)(7).…”

Section: Oelmentioning

confidence: 99%