Abstract:Clinical, histopathological, and laboratory evidence suggest that dancing eye syndrome/opsoclonus‐mycoclonus syndrome is an immune‐mediated and probably autoimmune disorder. There is a clear, but not invariable, association with neuroblastoma or ganglioneuroma in children, and with a miscellany of neoplasms in adults. Direct support, i.e. the identification of antibodies against cell‐surface antigens in neurons, is lacking but the nature of other evidence is such that the case for use of immunomodulatory thera… Show more
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