Abstract:The central nervous system (CNS) has long been considered as an immunological privileged site where the surveillance of the immune system does not reach out. However, it is now recognized that this CNS homeostasis is collapsed by neuroinflammation such as influx of proinflammatory factors and cells, neuronal dysfunction, and glial activation. Currently, CNS neuroinflammation is considered as a main pathomechanism to mediate disease progression in not only neurotrauma and neuroinflammatory disorders but also ne… Show more
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