Neuroimaging Pearls from theMDSCongress Video Challenge. Part 1: Genetic Disorders

Abstract

We selected several “imaging pearls” presented during the Movement Disorder Society (MDS) Video Challenge for this review. While the event, as implicated by its name, was video‐centered, we would like to emphasize the important role of imaging in making the correct diagnosis. We divided this anthology into two parts: genetic and acquired disorders. Genetic cases described herein were organized by the inheritance pattern and the focus was put on the imaging findings and differential diagnoses. Despite the overlapping phenotypes, certain described disorders have pathognomonic MRI brain findings that would provide either the “spot” diagnosis or result in further investigations leading to the diagnosis. Despite this, the diagnosis is often challenging with a broad differential diagnosis, and hallmark findings may be present for only a limited time.

The Most Illustrative Imaging Cases from the Video Challenge

“…We felt that this teaching material deserved to be disseminated more widely by the creation of an enduring document. Rather than focus on exotic cases, Dr. Lang and his colleagues have worked hard to select cases that have a significant educational value 1,2 …”

“…Rather than focus on exotic cases, Dr. Lang and his colleagues have worked hard to select cases that have a significant educational value. 1,2 As I retire from my role as a cohost of the Video Challenge, it is heartening to see that the effort put into the preparation of the event during the past 10 years is continuing to bear fruit. I am certain that the audience will find these cases to be valuable, and my hope is that ultimately this will benefit our patients.…”