Neuroimaging: Intrinsic Lesions of the Central Skull Base Region

Challenges in Histologic Diagnosis of Nonchordomatous Lesions of the Clivus

“…However, CT lacks sensitivity in evaluating bone marrow space involvement until significant marrow infiltration and subsequent trabecular bone loss has occurred. 13 Because of its superior contrast resolution, MRI is more sensitive in assessing bone marrow signal abnormalities in the skull base and in discriminating soft tissue. 14 Magnetic resonance imaging gives additional information about dural infiltration and the intracerebral origin of the tumor.…”

“…The findings may demonstrate lytic destruction of trabecular or cortical bone. 13 On MRI, there is a loss of normal marrow signal on precontrast T1-weighted sequences associated with heterogeneous T2 signal abnormalities and enhancement on the postcontrast T1-weighted scan. Associated extraosseous soft-tissue tumor generally demonstrates contiguous enhancement and can extend intracranially or extracranially.…”

“…Associated extraosseous soft-tissue tumor generally demonstrates contiguous enhancement and can extend intracranially or extracranially. 13 Chondromyxoid fibromas have been reported 15 to be isointense on T1-weighted images and hyperintense on T2-weighted images. Contrast enhancement can be dishomogeneous or mostly homogeneous.…”

Chordoma dedifferentiation after proton beam therapy: a case report and review of the literature

“…Diffusion-weighted MRI will show diffusion restriction, but this may be difficult to interpret in skull base tumors due to artifact at the skull base [ 30 ]. Contrast enhancement is variable [ 31 ]. Further advancements in molecular imaging may allow for definitive diagnosis without the need for biopsy.…”

Kafa Kaidesi Tumörleri

“…Sıklıkla karşımıza yumuşak doku bileşeni-nin eşlik ettiği ekspansil litik destrüktif olarak çıkarlar [12]. Yumuşak doku bileşeni genellikle BT'de hiperdens, T1A ve T2A görüntülerde ara intensitede izlenir.…”