Neuroimaging in refractory epilepsy. Current practice and evolving trends

Ramli, Norlisah; Rahmat, Kartini; Lim, Kheng Seang; Tan, Chong Tin

doi:10.1016/j.ejrad.2015.03.024

Cited by 9 publications

(9 citation statements)

References 59 publications

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“…Earlier studies have shown that around 20% of epilepsies have no lesion that is identified on MRI [1,11]. However, a study done on children having refractory epilepsy found that a high-resolution MRI was able to detect lesions not previously detected on a standard MRI in more than half of the cases [2].…”

Section: Dedicated Magnetic Resonance Imaging Sequences: Contributionmentioning

confidence: 97%

“…This is much easier to obtain when the lesion is well identified on brain imaging prior to the surgery [6]. Thus, neuroimaging is an essential step in the presurgical workup of localization-related epilepsies in order to well delineate the epileptogenic zone [2,7].…”

Section: Dedicated Magnetic Resonance Imaging Sequences: Contributionmentioning

confidence: 99%

“…MRI is considered to be the imaging modality of choice in defining the structural lesions that are responsible for seizures [5]. This is due to its better soft tissue contrast, multiplanar imaging and safety profile [2,10].…”

Section: Dedicated Magnetic Resonance Imaging Sequences: Contributionmentioning

confidence: 99%

“…However, epilepsy itself is a chronic condition in which seizures recur, and this can During the last decade, there have been many advances in our understanding and management of epilepsies. With the emerging neuroimaging modalities including specialized magnetic resonance imaging (MRI) sequences, the total number of presumed non-idiopathic cryptogenic partial epilepsies is drastically decreasing [1,2]. be complicated by neurobiological, cognitive, psychosocial, and occupational consequences [4,5].…”

Section: Introductionmentioning

confidence: 99%

“…The majority of epileptic patients are satisfactorily treated medically with antiepileptic drugs, but around 15-30% continue to have seizures despite therapy [2,4,5].…”

Section: Introductionmentioning

confidence: 99%

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Dedicated Magnetic Resonance Imaging Sequences: Contribution in the Diagnosis of Focal Epilepsy in the Lebanese Population

Jomaa¹,

Haddad²,

Adwane³

et al. 2018

JHS

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There have been many advances in the diagnosis and management of focal epilepsies particularly with neuroimaging techniques and magnetic resonance imaging (MRI). Special MRI sequences can be employed to localize and resect the epileptogenic lesions responsible for focal epilepsy. This study aims to show the benefit of dedicated epilepsy MRI sequences in the diagnosis of focal epilepsies. A general electric 1.5 Tesla MRI machine was used with standard and special sequences. Also, a Nihon Kohden electroencephalography (EEG) machine was used. This is a prospective observational study that included 51 patients with focal epilepsies who had an initial negative brain imaging. They underwent epilepsy MRI sequences along with a prolonged video EEG monitoring to localize the lesion, and then results were analyzed statistically using SPSS 22 program. The majority of patients were males (62.75%) with a mean age of 30 years. The grand majority of patients (74.5%, p value of 0.001) had their lesion localized by the epilepsy MRI. The most commonly found pathology was mesial temporal sclerosis. A significant number of patients (23.5%) were sent for an epilepsy surgery (p value 0.002). This study shows the significant impact of dedicated epilepsy MRI sequences on the diagnosis and management of focal epilepsy in the Lebanese population.

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Section: Dedicated Magnetic Resonance Imaging Sequences: Contributionmentioning

confidence: 97%

Section: Dedicated Magnetic Resonance Imaging Sequences: Contributionmentioning

confidence: 99%

Section: Dedicated Magnetic Resonance Imaging Sequences: Contributionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…The majority of epileptic patients are satisfactorily treated medically with antiepileptic drugs, but around 15-30% continue to have seizures despite therapy [2,4,5].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Dedicated Magnetic Resonance Imaging Sequences: Contribution in the Diagnosis of Focal Epilepsy in the Lebanese Population

Jomaa¹,

Haddad²,

Adwane³

et al. 2018

JHS

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Epilepsy surgery program in a resource‐limited setting in Vietnam: A multicentered collaborative model

Nguyen

et al. 2022

Epilepsia Open

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Objective: Although epilepsy surgery is more effective than medical therapy for drug-resistant patients, it is underutilized in both high-income and low-and middle-income countries. In light of our efforts to establish an epilepsy surgery program in a resource-limited setting, this study aimed to determine the outcome of the epilepsy surgery program in Ho Chi Minh City (HCMC), Vietnam. Methods:In 2018, we developed the HCMC epilepsy core multidisciplinary team with members from various hospitals and centers. The team typically included neurologists, neurosurgeons, neuropsychologists, psychiatrists, and nursing specialists. Presurgical evaluations were performed for patients with drug-resistant epilepsy, fulfilling the ILAE criteria, with an epileptogenic lesion (mesial temporal sclerosis, low-grade gliomas, or focal cortical dysplasia). All epilepsy surgeries were performed in two epilepsy surgery centers in HCMC between 2018 and 2021. The patients were followed up for at least 12 months.Results: Fifty-two patients with drug-resistant epilepsy underwent presurgical evaluation, of which 35 underwent surgery. Among the 52 patients, 20 (38.5%) underwent surgery after showing concordance among the results of standard presurgical assessments such as semiology, scalp interictal or ictal electroencephalography, and brain imaging. Among the 26 people with epilepsy who required more advanced evaluations, 15 underwent surgery with intraoperative electrocorticography to delineate the optimal resection borders.The outcomes of Engel Class I and Class II were achieved in 29/35 (82.8%) and 6/35 (17.2%) patients, respectively.

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Diagnosis of Epilepsy Disease with MRI Images Analysis and EEG Signal Processing

Shahraki

Irankhah

2022

Proceedings of the 2nd International Conference on Electronics, Biomedical Engineering, and Health Informatics

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Neuroimaging in refractory epilepsy. Current practice and evolving trends

Cited by 9 publications

References 59 publications

Dedicated Magnetic Resonance Imaging Sequences: Contribution in the Diagnosis of Focal Epilepsy in the Lebanese Population

Dedicated Magnetic Resonance Imaging Sequences: Contribution in the Diagnosis of Focal Epilepsy in the Lebanese Population

Epilepsy surgery program in a resource‐limited setting in Vietnam: A multicentered collaborative model

Diagnosis of Epilepsy Disease with MRI Images Analysis and EEG Signal Processing

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