Neuroimaging in Fetal Alcohol Spectrum Disorder

Adler, Richard S.

doi:10.1007/978-3-030-73628-6_7

Cited by 1 publication

(1 citation statement)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As the velocity of impulse propagation depends on the myelinization 76 this phenomenon can also justify our findings. This is one of the first, if not the first study toward exploring the role of QEEG in FASD diagnosis, as this research establishes a quantitative framework to detect QEEG findings, which may be characteristic for the FASD 21 . The study was limited by the absence of clinical data, especially the history of possible neglect or abuse and the results of neuropsychological tests.…”

Section: Discussionmentioning

confidence: 98%

Initial study on quantitative electroencephalographic analysis of bioelectrical activity of the brain of children with fetal alcohol spectrum disorders (FASD) without epilepsy

Bauer

Dyląg

Łysiak

et al. 2023

Sci Rep

View full text Add to dashboard Cite

Fetal alcohol spectrum disorders (FASD) are spectrum of neurodevelopmental conditions associated with prenatal alcohol exposure. The FASD manifests mostly with facial dysmorphism, prenatal and postnatal growth retardation, and selected birth defects (including central nervous system defects). Unrecognized and untreated FASD leads to severe disability in adulthood. The diagnosis of FASD is based on clinical criteria and neither biomarkers nor imaging tests can be used in order to confirm the diagnosis. The quantitative electroencephalography (QEEG) is a type of EEG analysis, which involves the use of mathematical algorithms, and which has brought new possibilities of EEG signal evaluation, among the other things—the analysis of a specific frequency band. The main objective of this study was to identify characteristic patterns in QEEG among individuals affected with FASD. This study was of a pilot prospective study character with experimental group consisting of patients with newly diagnosed FASD and of the control group consisting of children with gastroenterological issues. The EEG recordings of both groups were obtained, than analyzed using a commercial QEEG module. As a results we were able to establish the dominance of the alpha rhythm over the beta rhythm in FASD-participants compared to those from the control group, mostly in frontal and temporal regions. Second important finding is an increased theta/beta ratio among patients with FASD. These findings are consistent with the current knowledge on the pathological processes resulting from the prenatal alcohol exposure. The obtained results and conclusions were promising, however, further research is necessary (and planned) in order to validate the use of QEEG tools in FASD diagnostics.

show abstract

Section: Discussionmentioning

confidence: 98%