Neurogenic vasoconstriction of pial arterial vessels of various branching orders in normotensive and spontaneously hypertensive rats

Ryzhikova, O. P.; Shuvaeva, V. N.; Dvoretskii, D. P.

doi:10.1007/s10517-006-0079-2

Cited by 2 publications

(1 citation statement)

References 3 publications

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“…Hence, the "vascular regulation gradient" underlies the vasomotor regulation in the pia mater [4,6] in animals of all age groups; in other words, redistribution of the signi¿ cance of this or that regulatory mechanisms with changes in the vascular diameters. Myogenic EIDV reaction predominates in the 1st-3rd order arterial branches in adult animals, while the EDVD predominates in the 5th order vessels.…”

Section: Resultsmentioning

confidence: 99%

Age-Associated Characteristics of Vasomotor Regulation of the Pia Mater Arteries in Rats

Черток

Kotsyuba

2010

Bull Exp Biol Med

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The endothelium-dependent and myogenic reactions of pia mater arteries of the 1st-5th branching orders were studied in 1-, 3-, and 24-month-old rats by biomicroscopy method. The endothelium-independent (myogenic) reaction predominated in the 1st-3rd order branches and the endothelium-dependent vascular reaction in the 5th order branches of 3-month-old rats. Both regulatory mechanisms were equally developed in the 4th order branches. In 1-month-old rats, the endothelium-dependent reaction was more active in the majority of branches. In 24-month-old rats, this reaction was significantly higher than the endothelium-independent one only in the 4th and 5th order branches. In contrast to 3-month-old rats, the myogenic reaction of 24-month-old animals predominated in the 1st and 2nd order branches and the endothelium-dependent one in the 4th and 5th order branches. Vascular reactivity of 24-month-old rats was lower than in younger rats in all cases.

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Section: Resultsmentioning

confidence: 99%