Neurogenic heterotopic ossification after a stroke: diagnostic and radiological challenges

Acquired Neurogenic Heterotopic Ossification Following Treatment for ADEM: A Case Report and Literature Review

“…Treatment: Medical therapy and radiotherapy are available for the treatment and prophylaxis of HO. NSAIDs were recognized as the most effective drugs to prevent the formation of HO after surgery (1) . Most doctors agree that indomethacin is the best choice among NSAIDs not only prevent HO but also slows down the process of HO development.…”

“…Most doctors agree that indomethacin is the best choice among NSAIDs not only prevent HO but also slows down the process of HO development. However, the application of NSAIDs is relatively limited, for its adverse drug reaction such as gastrointestinal ulceration, decreased platelet aggregation and renal toxicity (1) . Coventry MB [22] et al conducted a research with patients who had HO following total hip arthroplasty, and they believed that radiation aids to prevent the formation of ectopic bone.…”

“…Progressive myositis ossificans: A rare genetic disease described since 1692 by Patin [1] 2. Traumatic myositis ossificans: The most frequent cause, through direct or surgical trauma 3.…”

Heterotopic Ossification – Complication or Chance?

“…Combined injuries to the skull and brain are generally referred to as "craniocerebral trauma" (CCT). In accordance with the Glasgow Coma Scale (GCS), mild, moderate and severe forms (3)(4)(5)(6)(7)(8) are distinguished, although there is also a classification based on morphological images in computed tomography (CT) [1]. The socioeconomic costs are enormousparticularly for severe CCTas the acute phase is followed by numerous complications that often require protracted rehabilitation [2].…”

Ulnar neuropathy due to heterotopic ossification: A rare complication after stroke

“…[1] Compared to other upper extremity complications, heterotopic ossification (HO) is extremely rare (0.5 to 1.2%) after stroke. [2] Heterotopic ossification is usually diagnosed about four months after stroke. The initial symptoms of HO are often loss of joint mobility and pain.…”