Neurofibrossarcoma retroperitoneal primário

Oliveira, Michelle Lucinda Gonçalves de; Filho, Gaspar de Jesus Lopes

doi:10.1590/s0100-69912003000500013

Cited by 1 publication

(4 citation statements)

References 4 publications

(11 reference statements)

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“…These patterns found in MRI can change depending on the arrangement of Antoni A and Antoni B areas; malignant schwannomas show intensity confluence in T1- and T2-weighted sequences. Although there are some features at the MRI, it cannot be used as specific standard to diagnose the disease[ 1 - 3 , 5 , 6 , 7 , 10 , 11 ]. Fibrosarcoma, liposarcoma and ganglioneuroma are differential diagnoses, which present similar pattern in CT and MRI[ 1 , 5 ].…”

Section: Discussionmentioning

confidence: 99%

“…Ultrasound- or CT-guided biopsy plays a key role in defining patients’ therapeutic plan in the preoperative period. Radio and/or chemotherapy are not recommended due to lack of tumor sensitivity to these treatments[ 1 , 2 , 4 , 6 , 7 , 11 ]. The only approach capable of confirming, and treating, patients’ condition lies on the surgical resection of the identified mass in order to subject it to reliable analysis, as well as to relief patients’ potential symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…Advanced stage schwannomas can be associated with abdominal pain or palpable abdominal tumor, and even with atypical symptoms such as secondary hypertension, hematuria, renal colic and headache[ 1 - 7 , 9 , 11 ]. Schwannomas are often benign; however, they can lead to malignant tumor transformation when they are associated with Von Recklinghausen’s disease[ 1 , 2 , 4 , 6 , 7 ]. It is necessary performing CT- or ultrasound-guided punch biopsy, with anatomopathological report, in order to confirm the preoperative diagnosis and start treatment[ 1 , 2 , 6 , 7 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

“…Schwannomas are often benign; however, they can lead to malignant tumor transformation when they are associated with Von Recklinghausen’s disease[ 1 , 2 , 4 , 6 , 7 ]. It is necessary performing CT- or ultrasound-guided punch biopsy, with anatomopathological report, in order to confirm the preoperative diagnosis and start treatment[ 1 , 2 , 6 , 7 , 11 ]. Surgical removal of the tumor is the treatment of choice, since schwannomas are not very sensitive to radiotherapy and/or che-motherapy[ 1 - 11 ].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Laparoscopic resection of primary retroperitoneal schwannoma: A case report

Ribeiro

Elias

Augusto

et al. 2020

WJCC

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BACKGROUND Schwannomas are rare, often benign, tumors deriving from Schwann cells that have low incidence in the retroperitoneal region (0.5% to 5%). Their diagnosis is hardly confirmed at early stage due to lack of specific features in signs, symptoms and imaging tests. Thus, it is necessary performing guided punch biopsy in order to identify it. Tumor removal is the treatment of choice due to its low sensitivity to radiation and chemotherapy. CASE SUMMARY Forty-seven years old female patient who was hospitalized for elective orthopedic procedure, without complications, evolved with severe pain in the lower limbs, thigh and gluteal region associated with neurogenic claudication. Persistent pain required magnetic resonance imaging (MRI) of the lumbar spine, which showed epidural collection with dural compression and massive heterogeneous perihepatic nodular lesion. The surgical team opted for draining the collection, as well as requested an MRI of the abdomen and pelvis, whose analysis showed expansive lesion in the retroperitoneum, in close contact with the inferior vena cava and with the right renal vein. A guided puncture was performed for diagnostic clarification, which showed immunohistochemical profile compatible with schwannoma. The selected treatment comprised retroperitoneum tumor resection in association with laparoscopic cholecystectomy. The patient was discharged and remained stable after 4-mo follow-up; she remains under follow-up to check the need of cancer investigations. CONCLUSION Schwannoma features requires surgical treatment based on laparoscopic resection, which often presents low relapse rates and optimistic prognosis.

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