Abstract:BACKGROUND
Neurofibromatosis type 1 (NF1) is characterized by café-au-lait patches on the skin and the presence of neurofibromas. Gastrointestinal stromal tumor (GIST) is the most common non-neurological tumor in NF1 patients. In NF1-associated GIST,
KIT
and
PDGFRA
mutations are frequently absent and imatinib is ineffective. Surgical resection is first-line treatment.
CASE SUMMARY
A 56-year-old woman with NF1 was hos… Show more
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