Neurofibromatosis and Neoplasms–two Interesting Cases

Abstract

Neurofibromatosis is an inherited disorder with varied systemic manifestations in the soft tissues, nervous system and skin. Cutaneous manifestations include multiple neurofibromas, café-au-lait macules, Lisch nodules and intertriginous freckling. Hematopoietic neoplasms like lymphomas and leukemias have been reported. We report here two interesting neoplasms associated with neurofibromatosis. The first case is a benign chondroid syringoma of the skin, occurring as a collision tumor in synchrony with neurofibroma. The second report is of a case of chronic myeloid leukemia in an adult with neurofibromatosis. Both cases are presented here for their rarity.