Neurofibromatosis and HIV in a pregnant woman

Pepe, F; Mininni, Claudia; Zambrotta, Elisa; Pepe, Gabriele; Rosa, Valeria La; Rosa, Rosario La; Insalaco, Giulio; Monteleone, Morena Maria

doi:10.22541/au.160315186.60167603/v1

2020

DOI: 10.22541/au.160315186.60167603/v1

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Neurofibromatosis and HIV in a pregnant woman

F Pepe¹,

Claudia Mininni²,

Elisa Zambrotta

et al.

Abstract: This a preprint and has not been peer reviewed. Data may be preliminary.

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“…The team should be prepared for severe and unpredictable maternal and fetal complications. Miscarriage can occur frequently, and the ongoing pregnancy may be complicated [56].…”

mentioning

confidence: 99%

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Reproductive Issues in Neurofibromatosis Type 1: An Update

2021

Archives of Obstetrics and Gynaecology

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Many factors have ameliorated prognosis for individual with NF1: higher knowledges and awareness on the disease, early diagnosis, better clinical counseling in reference centers, appropriate surveillance of symptoms, early surgical therapy in growing neurofibromas and better cosmetic treatment [3].There is an 8-15 years reduction in average life expectancy and malignancies and cardiovascular disease are the most frequent causes of death [8,9]. On 2,467 Danish patients with NF1 diagnosis, nerve and peripheral ganglia disease, pneumonia, epilepsy, bone and joint disorders, and intestinal infections were major contributors to the excess disease burden due to the disease [10]. Non-tumor symptoms contribute significantly to morbidity especially in relation to size, location of tumor/s and growth velocity

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“…The team should be prepared for severe and unpredictable maternal and fetal complications. Miscarriage can occur frequently, and the ongoing pregnancy may be complicated [56].…”

mentioning

confidence: 99%

“…Concerns for the mother are related to stroke (mostly hemorrhagic), acute vascular rupture (overall incidence of vascular anomalies is estimated (0.49-6.4%), hypertension, preeclampsia, low platelet count, HELLP syndrome and eclampsia [56,67,68]. Particularly hypertension due to pheochromocytoma may change the prognosis for the mother and the fetus [69].…”

mentioning

confidence: 99%

Reproductive Issues in Neurofibromatosis Type 1: An Update

2021

Archives of Obstetrics and Gynaecology

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Neurofibromatosis and HIV in a pregnant woman

Abstract: This a preprint and has not been peer reviewed. Data may be preliminary.

Cited by 1 publication

References 12 publications

Reproductive Issues in Neurofibromatosis Type 1: An Update

Reproductive Issues in Neurofibromatosis Type 1: An Update

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