Neurofibroma like nodules on shoulder: First sign of gastric adenocarcinoma

Karakoca, Y.; Aslan, Canan; Erdemir, Aslı Turgut; Kiremitçi, Ümmühan; Gürel, Mehmet Salih; Huten, Osman

doi:10.5070/d379q944rb

Cited by 7 publications

(1 citation statement)

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“…Cutaneous metastases of GC may appear on the abdomen, face, scalp, chest, back, neck, and extremities. 13 – 16 Lesions typically manifest as single or multiple red to violaceous nodules, though they may also present as cellulitis-like or erysipelas-like plaques. 9 – 11 On histologic examination, signet ring cells may be an important clue.…”

Section: Discussionmentioning

confidence: 99%

Metastatic gastric adenocarcinoma to the cutaneous neck and chest wall

Murphy,

Wang,

Wachuku

et al. 2024

SAGE Open Medical Case Reports

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This case describes an atypical cutaneous presentation of metastatic gastric carcinoma in a patient initially presenting with dysphagia and a sclerotic red plaque overlying the anterior neck and chest. Skin biopsy revealed metastatic adenocarcinoma from the upper gastrointestinal tract. Esophagogastroduodenoscopy revealed stage IV metastatic gastric adenocarcinoma. Treatment with chemotherapy was initiated.

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Section: Discussionmentioning

confidence: 99%

Metastatic gastric adenocarcinoma to the cutaneous neck and chest wall

Murphy,

Wang,

Wachuku

et al. 2024

SAGE Open Medical Case Reports

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Cutaneous metastasis from gastric cancer: Manifestation, diagnosis, treatment and prognosis

Yao,

Tao,

Fan

2024

European Journal of Surgical Oncology

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Cutaneous Metastases From Internal Malignancies

Alcaraz

Cerroni

Rütten

et al. 2012

The American Journal of Dermatopathology

221

104

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Skin metastases occur in 0.6%-10.4% of all patients with cancer and represent 2% of all skin tumors. Skin metastases from visceral malignancies are important for dermatologists and dermatopathologists because of their variable clinical appearance and presentation, frequent delay and failure in their diagnosis, relative proportion of different internal malignancies metastasizing to the skin, and impact on morbidity, prognosis, and treatment. Another factor to take into account is that cutaneous metastasis may be the first sign of clinically silent visceral cancer. The relative frequencies of metastatic skin disease tend to correlate with the frequency of the different types of primary cancer in each sex. Thus, women with skin metastases have the following distribution in decreasing order of frequency of primary malignancies: breast, ovary, oral cavity, lung, and large intestine. In men, the distribution is as follows: lung, large intestine, oral cavity, kidney, breast, esophagus, pancreas, stomach, and liver. A wide morphologic spectrum of clinical appearances has been described in cutaneous metastases. This variable clinical morphology included nodules, papules, plaques, tumors, and ulcers. From a histopathologic point of view, there are 4 main morphologic patterns of cutaneous metastases involving the dermis, namely, nodular, infiltrative, diffuse, and intravascular. Generally, cutaneous metastases herald a poor prognosis. The average survival time of patients with skin metastases is a few months. In this article, we review the clinicopathologic and immunohistochemical characteristics of cutaneous metastases from internal malignancies, classify the most common cutaneous metastases, and identify studies that may assist in diagnosing the origin of a cutaneous metastasis.

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Neurofibroma like nodules on shoulder: First sign of gastric adenocarcinoma

Cited by 7 publications

References 0 publications

Metastatic gastric adenocarcinoma to the cutaneous neck and chest wall

Metastatic gastric adenocarcinoma to the cutaneous neck and chest wall

Cutaneous metastasis from gastric cancer: Manifestation, diagnosis, treatment and prognosis

Cutaneous Metastases From Internal Malignancies

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