Neuroendocrine stress response in Atlantic salmon (Salmo salar) and Coho salmon (Oncorynchus kisutch) during sea lice infestation

Vargas‐Chacoff, Luis; Muñoz, José Luis Pedraz; Saravia, Julia; Oyarzún, R.; Pontigo, Juan Pablo; González, Margarita P.; Mardones, O.; Hawes, Christopher; Pino, Jorge A.; Wadsworth, Simón; Morera, Francisco J.

doi:10.1016/j.aquaculture.2019.04.046

Cited by 13 publications

(8 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Among them, ω-3 polyunsaturated fatty acids potentially affect hepatic lipid metabolism, improve antioxidation, regulate in ammation, and prevent cell block and apoptosis [20,21]. Compared with Atlantic salmon, Coho salmon has a shorter aquaculture cycle and tougher skin, exhibiting relatively stronger resistance against sh lice and infectious salmon anemia [22,23]. Hence, Coho salmon has emerged as one of our country's most favored salmon species in aquaculture.…”

Section: Introductionmentioning

confidence: 99%

WITHDRAWN: Effects of dietary Bacillus pumilus on the growth performance, intestinal health, lipid metabolism, and mTOR signaling pathway of juvenile Coho salmon (Oncorhynchus kisutch)

Guo,

Meng,

et al. 2024

Preprint

View full text Add to dashboard Cite

This study explored and evaluated the addition of the probiotic Bacillus pumilus Rf8 to Coho salmon (Oncorhynchus kisutch) feed. A total of 360 juvenile Coho salmon with an initial body weight of 130.45 ± 1.11 g were randomly divided into four treatment groups, with three replicates per group and 30 fish per replicate. Different concentrations of B. pumilus were added to the feed of the four treatment groups: 0 (control group), 2 × 106, 4 × 108, and 8 × 1010 cfu/g. The experiment lasted 70 days. Growth performance parameters, nutritional metabolism, immune-related serum biochemical indicators, enzyme activity, gene expression, and muscle composition were evaluated. Furthermore, intestinal histology and intestinal flora were assessed. The findings indicated that relative to the control group, B. pumilus Rf8 notably enhanced the growth performance, protein and fat metabolism, and immune status of the fish, effectively bolstering the structure and function of the intestinal microbiota. The “4 × 108 cfu/g concentration” group demonstrated a substantial advantage in juvenile fish. The B. pumilus strains identified in this study exhibit promising potential as probiotic feed supplements in Coho salmon aquaculture.

show abstract

Section: Introductionmentioning

confidence: 99%

WITHDRAWN: Effects of dietary Bacillus pumilus on the growth performance, intestinal health, lipid metabolism, and mTOR signaling pathway of juvenile Coho salmon (Oncorhynchus kisutch)

Guo,

Meng,

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Lice infestation induces stress and leads to an increase in cortisol and heat shock proteins (HSPs) 60, 70, and 90 [ 34 , 35 ]. HSPs are involved in different signaling cascades, and can play roles in modulating inflammatory responses [ 36 ].…”

Section: Resultsmentioning

confidence: 99%

Sea Lice (Lepeophtheirus salmonis) Infestation Reduces the Ability of Peripheral Blood Monocytic Cells (PBMCs) to Respond to and Control Replication of Salmonid Alphavirus in Atlantic Salmon (Salmo salar L.)

Gamil

Gadan

Gislefoss

et al. 2020

Viruses

View full text Add to dashboard Cite

Here we have studied the impact of lice (Lepeophtheirus salmonis) infestation of donor fish on the ability of isolated peripheral blood monocytes (PBMCs) to control the replication of salmonid alphavirus (SAV) ex vivo. PBMCs were collected by Percoll gradients at eight and nine weeks post copepodid infestation of Atlantic salmon post smolt. Uninfested fish were controls. PBMCs were then infected ex vivo with SAV (subtype 3), and samples were collected for analysis at two, four, and six days post virus infection. Virus titer in the supernatant was assayed in CHH-1 cells, and in addition, the relative expression of the virus structural protein E2 and selected host antiviral genes, IRF9, ISG15, Mx, and IFIT5, were assayed using real-time PCR. Significantly higher virus replication was detected in cells collected from lice-infested fish compared to controls. Higher virus titer coincided with an inability to upregulate the expression of different immune genes, IFIT5, IRF9, and Mx. These findings point towards compromised ability of PBMCs from lice-infested fish to control virus replication, and, to our knowledge, is the first report showing the direct effect of lice infestation on the interplay between viruses and immune cells. There is a possible impact on the dynamic spread of viral diseases in the aquatic environment.

show abstract

“…For example, the ectoparasite Caligus rogercresseyi Boxshall and Bravo, 2000 affects the Chilean salmon industry as it infests primarily Atlantic salmon ( Salmo salar Linnaeus, 1758), but not Coho salmon ( Oncorhynchus kisutch (Walbaum, 1792)), which appears to be immune to infestation by this crustacean ( Valenzuela-Muñoz et al, 2016 ). Comparative studies of these host-parasite systems also demonstrated that the better adapted O. kisutch has a considerably lower cortisol release than the less well adapted S. salar following infestation with C. rogercresseyi ( Vargas-Chacoff et al, 2019 ).…”

Section: Discussionmentioning

confidence: 99%

Mutual adaptations between hosts and parasites determine stress levels in eels

Honka

Sures

2021

International Journal for Parasitology: Parasites and Wildlife

View full text Add to dashboard Cite

Invasive parasites may severely affect their new hosts. Two invasive parasites occurring in the European eel ( Anguilla anguilla ) are the Asian swim bladder nematode Anguillicola crassus and the Ponto-caspian acanthocephalan Pomphorhynchus sp., which were introduced to the river Rhine in the early 1980/90s. The Japanese eel ( Anguilla japonica ), as the native host of A. crassus , developed mutual adaptations to the swim bladder parasite, which are lacking in the European eel. Therefore, after its spread to Europe, infestations of European eels with A. crassus were found to be more severe and caused massive swim bladder wall damages mainly due to the feeding activity of the adult nematodes. A suppression of the immune system also appears to be likely, which allows secondary infections e.g. by bacteria or other parasites in European eels. Acanthocephalans of the genus Pomphorhynchus have not been described so far in Japanese eels, in contrast to European eels, which regularly show infestations with Pomphorhynchus sp. By using these differentially adapted host-parasite associations for experimental studies, host stress responses were examined in the present study in relation to the degree of mutual adaptations between eel hosts and parasites. Under laboratory conditions, Japanese and European eels were each inoculated with A. crassus and Pomphorhynchus sp., respectively, to investigate their stress responses against differently adapted parasites. The stress response was determined by analyzing plasma levels of cortisol, which is the main corticosteroid hormone during stress response of fish. The results show a strong cortisol release in European eels after infestation with A. crassus whereas Japanese eels only react against Pomphorhynchus sp. infestations. These results are consistent with the initial hypothesis that a low degree of host-parasite adaptations lead to stronger host stress responses against the parasite.

show abstract

Neuroendocrine stress response in Atlantic salmon (Salmo salar) and Coho salmon (Oncorynchus kisutch) during sea lice infestation

Cited by 13 publications

References 57 publications

WITHDRAWN: Effects of dietary Bacillus pumilus on the growth performance, intestinal health, lipid metabolism, and mTOR signaling pathway of juvenile Coho salmon (Oncorhynchus kisutch)

WITHDRAWN: Effects of dietary Bacillus pumilus on the growth performance, intestinal health, lipid metabolism, and mTOR signaling pathway of juvenile Coho salmon (Oncorhynchus kisutch)

Sea Lice (Lepeophtheirus salmonis) Infestation Reduces the Ability of Peripheral Blood Monocytic Cells (PBMCs) to Respond to and Control Replication of Salmonid Alphavirus in Atlantic Salmon (Salmo salar L.)

Mutual adaptations between hosts and parasites determine stress levels in eels

Contact Info

Product

Resources

About