Neuroendocrine Neoplasms of the Lung

Borczuk, Alain C.

doi:10.1016/b978-0-323-44284-8.00014-4

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2020

2022

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Cited by 3 publications

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“…Other laboratory tests: Plasma serotonin concentration and urinary excretion of serotonin are very less commonly used biochemical tests [29]. Blood/ urine serotonin levels are not recommended as a standard diagnostic test as the end product of the serotonin metabolism is 5-HIAA [30].…”

Section: Laboratorymentioning

confidence: 99%

Carcinoid Syndrome: A Review

Gade¹,

Olariu²,

Douthit³

2020

Cureus

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Carcinoid syndrome (CS) is a paraneoplastic syndrome caused by the release of serotonin and other substances from well-differentiated neuroendocrine tumors (NETs). The hallmark symptoms of carcinoid syndrome are flushing and diarrhea; atypical signs and symptoms can include wheezing, abdominal pain, valvular heart disease, telangiectasias, pellagra, and the complications of mesenteric fibrosis, including ureteral obstruction, bowel obstruction, and bowel ischemia. These symptoms are mediated by the release of serotonin (5-HT), histamine, kallikrein, prostaglandins, and tachykinins. The diagnosis of CS requires these symptoms and corresponding elevations in lab tests. Treatment options include surgery and medical management with somatostatin analogs.

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Section: Laboratorymentioning

confidence: 99%