Neuroendocrine consequences of very early weaning in swine

Hay, Magali; Orgeur, P.; Lévy, Frédéric; Dividich, Jean Le; Concordet, Didier; Nowak, Raymond; Schaal, Benoı̂st; Mormède, Pierre

doi:10.1016/s0031-9384(00)00404-2

Cited by 35 publications

(26 citation statements)

References 34 publications

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“…Nucleotide supplementation may have contributed to spare, during the critical transition phase of weaning, the cost of de novo nucleotide synthesis and/or salvage pathway (Burrin and Stoll, 2002). Voluntary feed intake in post-weaning has a deep effect on the functioning of several neuroendocrine systems (Carroll et al, 1998;Hay et al, 2001). Although we observed the same voluntary feed intake between groups, a different hormonal response occurred during the first 2 weeks after weaning.…”

Section: Discussionmentioning

confidence: 99%

Effects of dietary nucleotide supplementation on growth performance and hormonal and immune responses of piglets

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Saleri

Borghetti

et al. 2012

Animal

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The effects of dietary nucleotide supplementation from 9 days of age until the end of post-weaning on piglets hormonal and immune responses and on growth performance were investigated. During lactation (days 9 to 21) and post-weaning (days 22 to 55) 10 [HBI Fomeva11 3 (Large White 3 Landrace)] litters (n 5 108 piglets) had ad libitum access to two standard diets, both supplemented with 0% (T0 group) or 0.1% (T1 group) of yeast extract nucleotides. BW of piglets at days 21 (P , 0.10), 35 and 55 (P , 0.05) was greater in T1 compared with T0. Feed intake was not different between groups (P . 0.05). Cortisol content was lower in T1 than in T0 at days 28 and 35 (P , 0.05), whereas growth hormone was lower at day 35 (P , 0.05). Levels of IGF-1 were similar across groups (P . 0.05). Nucleotide-supplemented diets increased lymphocyte subpopulation CD42CD81 high at days 21 and 35 (P , 0.05), whereas CD41CD82 cells were higher in T1 than in T0 at day 21 (P , 0.05). Peripheral blood mononuclear cells cytokine expression was influenced by dietary nucleotide supplementation. At weaning, interleukin (IL)-6 and IL-1b expression was lower (P , 0.05) in T1 compared with T0, whereas the expression of interferon (IFN)-g and IL-10 was higher (P , 0.05). At day 28, piglets in T1 showed higher values of tumor necrosis factor (TNF)-a expression than T0 and lower values of IL-10 expression (P , 0.05). Dietary nucleotide supplementation had a suppressive effect on IL-6 and IL-10 expression (P , 0.05) at day 35. On the contrary, the expression of IFN-g, TNF-a and IL-1b was enhanced (P , 0.05). In conclusion, these results suggest that starting a dietary nucleotide supplementation before weaning can improve the adaptive capabilities of weaned piglets to the stressors, enhancing the growth performance.

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Section: Discussionmentioning

confidence: 99%

Effects of dietary nucleotide supplementation on growth performance and hormonal and immune responses of piglets

Superchi

Saleri

Borghetti

et al. 2012

Animal

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“…On the other hand, urinary noradrenaline levels dropped dramatically and remained low to reach control levels at 28 days of age only. This change may be related to the deficit in energy intake [6].…”

Section: Discussionmentioning

confidence: 99%

“…Finally, mother young separation induces important behavioural and growth rate perturbations associated with an elevation of urinary cortisol level [6] which indicate a psychological traumatic. This social stress The evolution of these behaviours parallels belly-nosing.…”

Section: Discussionmentioning

confidence: 99%

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Behavioural, growth and immune consequences of early weaning in one-week-old Large-White piglets

et al. 2001

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-Genetic improvement in sows' prolificity is limited by their milk capacities, which do not allow all piglets to survive or grow normally. This experiment compared the behaviour, growth and immune responses of piglets that were weaned early at 6 days of age (EW) vs. control Large White piglets' (C) suckled by their mothers. Behaviour of 9 litters of 5 to 8 piglets in each group were observed from d5 to d20. All piglets were weighed from birth to d74. Three piglets from each group were slaughtered on d36 for immunological analysis. Until they began to eat dry food, EW piglets walked and vocalised more than C piglets. After that time, when resting, they were less often lying down and more frequently in contact with littermates under the heater. Aggressive behaviour and bellynosing were more frequent. They displayed a more marked growth check after weaning than did C piglets until 28 days of age. In EW piglets, at 36 days of age, there was a higher density of T-and B-lymphocytes in the gut epithelium and lamina propria, respectively, in relation to the size of lymphoid follicles of Peyer's patches. The results indicate great behavioural adaptation capacities of very early-weaned piglets, together with earlier maturation of their gut immune system. pig / weaning / behaviour / immunology / welfareRésumé -Conséquences sur le comportement, la croissance et le système immunitaire, d'un sevrage à l'âge d'une semaine, chez des porcelets Large-White. Les capacités laitières limitées des truies hyperprolifiques ne permettent pas à tous les porcelets de survivre ou de croître normalement. L'objectif de cette étude est de mesurer les paramètres comportementaux, zootechniques et immunologiques, exprimés par des porcelets Large-White sevrés ultra-précocement (EW) à 6 jours et des porcelets témoins (C) allaités par leur mère. Les comportements de 9 portées de 5 à 8 porcelets EW Reprod. Nutr. Dev. 41 (2001) [321][322][323][324][325][326][327][328][329][330][331][332] 321

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“…Loading density is another important aspect of animal transport, for it has been shown that both too little and too much vital space per animal can compromise health and welfare (Hay et al 2001;Kanitz et al 2002). For this reason, the space requirement during transport is not only a problem of animal health but also a welfare concern throughout the pork industry.…”

Section: Loading Densitymentioning

confidence: 99%

Stressor factors in the transport of weaned piglets: a review

et al. 2013

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ABSTRACT:The transport of weaned piglets is considered an important stress factor since the conditions involved in shipping affect the animals' health and welfare. The principal stressor factors that piglets experience during transport include: mixing with unfamiliar animals, overcrowding, heat, cold, temperature fluctuations, vibrations, and noise. It is well known that all these factors contribute to raising the level of stress caused by the weaning process; however, the additional effects attributable to transport immediately after weaning impact the physiology, metabolism and behaviour of piglets, predisposing them to delayed growth. For this reason, animal transport must be well-planned and take into account such aspects as preparation of the piglets, choosing the best route and vehicle type, assuring adequate vehicle design and maintenance, and providing sufficient space. Also important for assuring the welfare of the piglets during transport are sufficient rest time, appropriate access to food and water, defined measures for monitoring the animals during the trip, implementing means of disease control, and establishing the steps to be followed in case of an emergency.

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Neuroendocrine consequences of very early weaning in swine

Cited by 35 publications

References 34 publications

Effects of dietary nucleotide supplementation on growth performance and hormonal and immune responses of piglets

Effects of dietary nucleotide supplementation on growth performance and hormonal and immune responses of piglets

Behavioural, growth and immune consequences of early weaning in one-week-old Large-White piglets

Stressor factors in the transport of weaned piglets: a review

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