Neurocysticercosisnew millennium, ancient disease and unending debate

Narula, Gaurav; Bawa, KS

doi:10.1007/bf02723590

Cited by 5 publications

(3 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These 92 publications were further categorized in terms of how “weight of evidence” was defined. ( 4–95 ) Reference lists of these articles were reviewed to identify additional relevant documents (e.g., risk assessment guidelines from the Environmental Protection Agency ( 96–98 ) and other government agencies as well as classic methodologic articles (e.g., Austin Bradford Hill's classic 1965 article ( 99 ) on causation)). These were used throughout the text for illustrative purposes.…”

Section: Methodsmentioning

confidence: 99%

Weight of Evidence: A Review of Concept and Methods

2005

View full text Add to dashboard Cite

"Weight of evidence" (WOE) is a common term in the published scientific and policy-making literature, most often seen in the context of risk assessment (RA). Its definition, however, is unclear. A systematic review of the scientific literature was undertaken to characterize the concept. For the years 1994 through 2004, PubMed was searched for publications in which "weight of evidence" appeared in the abstract and/or title. Of the 276 papers that met these criteria, 92 were selected for review: 71 papers published in 2003 and 2004 (WOE appeared in abstract/title) and 21 from 1994 through 2002 (WOE appeared in title). WOE has three characteristic uses in this literature: (1) metaphorical, where WOE refers to a collection of studies or to an unspecified methodological approach; (2) methodological, where WOE points to established interpretative methodologies (e.g., systematic narrative review, meta-analysis, causal criteria, and/or quality criteria for toxicological studies) or where WOE means that "all" rather than some subset of the evidence is examined, or rarely, where WOE points to methods using quantitative weights for evidence; and (3) theoretical, where WOE serves as a label for a conceptual framework. Several problems are identified: the frequent lack of definition of the term "weight of evidence," multiple uses of the term and a lack of consensus about its meaning, and the many different kinds of weights, both qualitative and quantitative, which can be used in RA. A practical recommendation emerges: the WOE concept and its associated methods should be fully described when used. A research agenda should examine the advantages of quantitative versus qualitative weighting schemes, how best to improve existing methods, and how best to combine those methods (e.g., epidemiology's causal criteria with toxicology's quality criteria).

show abstract

Section: Methodsmentioning

confidence: 99%

Weight of Evidence: A Review of Concept and Methods

2005

View full text Add to dashboard Cite

show abstract

“…Use of albendazole has attracted plenty of controversy and several studies have been conducted to answer the question whether cysticidal treatment makes any difference or not. The facts which favor its use are; its effective penetration into brain tissue; reduction in the number of generalized seizures; faster resolution of cysts in brain after therapy, decrease in the burden of parasites; it is inexpensive and associated with minimal toxicity [21,22]. Given these advantages, we recommend albendazole therapy for 4 weeks in all patients having 1-2 cysts, provided they are not strategically situated (brainstem or ventricles etc.…”

Section: Discussionmentioning

confidence: 99%

Clinical pleomorphism of neurocysticercosis in children: Some unusual manifestations

Jha

Kumar

2015

J Pediatr Neurol

View full text Add to dashboard Cite

Neurocysticercosis (NCC) is a major public health problem as it is the most common helminthic infestation of the central nervous system in developing countries. Clinical manifestations are nonspecific and pleomorphic, but case reports on uncommon presentations of NCC in children are relatively few. We report four cases of NCC in children, with unusual clinical presentations, which exhibit the spectrum of clinical pleomorphism. These include cases presenting with syndrome of cerebellar ataxia, focal dystonia, stroke and dementia. Their clinical details and possible mechanism for these uncommon presentations are also discussed. Thus, a high level of suspicion should be kept for NCC, especially in endemic zones and developing countries. It is important that neurologists become familiar with this disorder, as they are involved in the diagnosis and management of NCC and will play an important role in efforts to control the disease.

show abstract

“…Del Brutto's diagnostic classification relied on the ETIB as major criterion, which did not hold the test of time. Due to its complexity and difficulties in clinical and epidemiological application, Narula and Bawa classified NCC [4] based on clinical and neuroimaging studies. (Figs.…”

Section: Neuroimagingmentioning

confidence: 99%