Neurocysticercosis — A review of 231 cases

Monteiro, L.; Coelho, Teresa; Stocker, A.

doi:10.1007/bf01711064

Cited by 45 publications

(28 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Epileptic seizures, hydrocephaly and intracranial hypertension, in this order, are the most frequent clinical features. This pleomorphic disease is a result of the presence of the parasite itself (cysticerci), the inflammatory process that surrounds the larvae, and the residual fibrosis and calcification (5,6).…”

mentioning

confidence: 99%

Interleukin-5 and interleukin-10 are major cytokines in cerebrospinal fluid from patients with active neurocysticercosis

Rodrigues

de-Mello

Magalhães

et al. 2000

Braz J Med Biol Res

View full text Add to dashboard Cite

Neurocysticercosis (NCC) is a common neurological disorder especially in developing countries, caused by infection of the brain with encysted larvae of the tapeworm Taenia solium. Seizures are a common finding associated with this disease. The objective of the present study was to evaluate the correlation between the levels of various cytokines present in the cerebrospinal fluid (CSF) of patients with NCC and the severity of the disease. The levels of the cytokines IL-1ß, TNF-a, IL-5, IL-10 and IFN-g were determined in the CSF of 22 patients with active NCC, 13 patients with inactive NCC and 15 control subjects. CSF from patients with active NCC presented significantly higher IL-5 levels compared to control subjects. IL-5 and IL-10 levels in CSF from NCC patients with inflammatory CSF were significantly higher than those detected in non-inflammatory CSF. These results show a predominant Th2 lymphocyte activation in human NCC and also indicate the possible use of cytokines in the CSF as a marker for the differential diagnosis between inactive disease and the active form of NCC.

show abstract

mentioning

confidence: 99%

Interleukin-5 and interleukin-10 are major cytokines in cerebrospinal fluid from patients with active neurocysticercosis

Rodrigues

de-Mello

Magalhães

et al. 2000

Braz J Med Biol Res

View full text Add to dashboard Cite

show abstract

“…In fact, the data presented in that work refers to publications from the 1990s and from a study in a geographically restricted area in the north of Portugal [18]. However, clinicians must be aware that NCC can be diagnosed in persons born in nonendemic areas, and in such cases it is crucial to search for a household contact with a tapeworm infection.…”

Section: Discussionmentioning

confidence: 99%

A case of imported neurocysticercosis in Portugal

Valadas

Badura

Marques

et al. 2015

J Infect Dev Ctries

View full text Add to dashboard Cite

Neurocysticercosis (NCC) is the most common cause of acquired epilepsy in resource-poor countries. We report the case of a 24-year-old woman born and residing in Guinea-Bissau, who was transferred to Portugal two months after the onset of a possible meningitis (fever, headache, seizures, and coma) that did not respond to antibiotic treatment. The diagnosis of NCC was confirmed by MR imaging, which showed multiple lesions compatible with cysticercus, and by polymerase chain reaction (PCR) of the cerebrospinal fluid. After 28 days on albendazole and dexamethasone without improvement, she was started on praziquantel, which she completed in six weeks with progressive recovery.

show abstract

“…In a 12-year period data analysis of subacute to chronic meningitis cases from South India, anti-mycobacterial antibodies and anti-Cysticercus antibodies were found in 35.4% and 5.47% of the cases of NCC respectively 2 . NCC presenting as chronic meningitis is also being reported from Italy 12 , Brazil 1 , Portugal 16 , Korea 3,28 , and other endemic parts of the World 10,12,20,21 .…”

mentioning

confidence: 94%

Detection of Cysticercus antigens and antibodies in cerbrospinal fluid of patients with chronic meningitis

Parija

Sahu

Dhanya

2007

Rev. Inst. Med. trop. S. Paulo

View full text Add to dashboard Cite

SUMMARYChronic meningitism is a less frequent manifestation of neurocysticercosis caused by Taenia solium cysticerci. In the present study we used Co-agglutination (Co-A), a simple and rapid slide agglutination test to detect specific Cysticercus antigen in the 67 cerebrospinal fluid (CSF) samples from patients with chronic meningitis of unknown etiology. The results were compared with that of ELISA for detection of antibodies. Among these samples four (5.97%) were positive for Cysticercus antigen by Co-A test and six (8.95%) were positive for antibodies by ELISA. Two samples were positive by both Co-A and ELISA, two were positive only by Co-A and four were positive only by ELISA. In the present study, although Cysticercus antigen and antibodies were present in CSF samples from eight (11.94%) patients, we cannot affirm that all the cases of chronic meningitis are due to cysticercosis, but for any case of chronic meningitis of unknown origin, it would be useful to consider the possibility of cysticercal meningitis.

show abstract

Neurocysticercosis — A review of 231 cases

Cited by 45 publications

References 31 publications

Interleukin-5 and interleukin-10 are major cytokines in cerebrospinal fluid from patients with active neurocysticercosis

Interleukin-5 and interleukin-10 are major cytokines in cerebrospinal fluid from patients with active neurocysticercosis

A case of imported neurocysticercosis in Portugal

Detection of Cysticercus antigens and antibodies in cerbrospinal fluid of patients with chronic meningitis

Contact Info

Product

Resources

About