Neurocognitive fitness in the sub-acute stage after mild TBI: The effect of age

Stapert, Sven; Houx, Peter J.; Kruijk, Jelle de; Ponds, Rudolf; Jolles, Jelle

doi:10.1080/02699050500442949

Cited by 18 publications

(3 citation statements)

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“…Therefore, even patients initially diagnosed with a "mild" head injury may experience complicated neurological and/or general physical injuries associated with poorer prognosis or functional outcome (Iverson, 2005). Conversely, other MTBI studies have used more conservative criteria for participant selection (e.g., Stapert et al, 2006) or have excluded participants with abnormal head CT (Sheedy et al, 2006). Variability in MTBI definition used and inclusion/exclusion criteria employed by researchers may create additional heterogeneity in published findings.…”

Section: Mild Tbimentioning

confidence: 78%

A Multidisciplinary Evaluation of Traumatic Brain Injury: Early Predictors of Outcome

Dischinger¹

2007

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Public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing this collection of information. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing this burden to Department of Defense, Washington Headquarters Services, Directorate for Information Operations and Reports (0704-0188), 1215 Jefferson Davis Highway, Suite 1204, Arlington, VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to any penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. REPORT DATE (DD-MM-YYYY) 01-04-20072. REPORT TYPE (From -To) Final DATES COVERED PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBERUniversity of Maryland, Baltimore Baltimore, Maryland 21203-6428 SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR'S ACRONYM(S) U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 SPONSOR/MONITOR'S REPORT NUMBER(S) DISTRIBUTION / AVAILABILITY STATEMENTApproved for Public Release; Distribution Unlimited SUPPLEMENTARY NOTES ABSTRACTThis is the final report of a follow-up study of 180 subjects with Mild TBI who were treated at a Level I Trauma Center. The goal of the study was: 1) to describe the natural history of Mild TBI and 2) to identify factors that best predict long term sequelae. Most symptoms increased within 3-10 day post-injury decreased again by 3 months. Although physical symptoms had the highest prevalence, most returned to pre-injury levels by 3 months. Emotional and cognitive symptoms, however, remained elevated. Overall, approximately 36% of patients still reported four or more symptoms (defined as post-concussive syndrome, PCS), even one year after their injury. Post-injury emotional symptoms were the strongest predictors of PCS. Also, women and older patients were at higher risk of PCS. Balance problems, as assessed by balance testing, were associated with noise sensitivity, perhaps indicative of vestibular problems. In addition, while not all patients had balance testing, due to the presence of other injuries, noise sensitivity was significantly associated with subjects' inability to return to work or school at one year post-injury. The simple reaction time measure from ANAM did not predict PCS. There was no association between post-injury S100β levels and long term sequelae. SUBJECT TERMS INTRODUCTIONEach year approximately 1.5 million Americans sustain a traumatic brain injury (TBI). The most common causes of TBI are due to blunt force trauma. The goal of this research was to identify a cohort of patients with mild TBI and follow them for a period of one year (1) to...

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Section: Mild Tbimentioning

confidence: 78%

A Multidisciplinary Evaluation of Traumatic Brain Injury: Early Predictors of Outcome

Dischinger¹

2007

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“…96 Neuropsychological assessment is especially important in distinguishing the unique patterns of impairments that older adults exhibit after TBI. 97,98 EPILEPSY Literature search showed >1680 peer-reviewed studies on neuropsychological function and epilepsy. Neuropsychological assessment is well established as a critical variable in the evaluation and treatment of epilepsy, particularly refractory epilepsy when surgery is being considered.…”

Section: Strokementioning

confidence: 99%

Neuropsychological Assessment

Braun

Tupper

Kaufmann

et al. 2011

Cognitive and Behavioral Neurology

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For both children and adults with neurological, neurodevelopmental, medical, or psychiatric disorders, neuropsychological assessment can be a valuable tool in determining diagnosis, prognosis, and functional abilities as well as informing clinical management. This review summarizes the contributions of neuropsychological assessment to clinical care across diagnostic categories, with the goal of helping clinicians determine its utility for individual patients.

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“…3 TBI often results in lifelong impairments in physical, cognitive, and psychosocial function, even in socalled "mild" cases. 4,5 A substantial proportion (29%) of individuals who sustain mild TBI also experience "persistent postconcussive syndrome," in which neurocognitive deficits and emotional symptoms persist beyond 12 months' postinjury. 6 The most common psychiatric disturbances following TBI include major depression, anxiety, personality and neurobehavioral changes such as impulsivity, aggressiveness, as well as substance abuse.…”

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confidence: 98%