Neuroblastoma in childhood: review and radiological findings

Abstract

The natural history, biologic and histological features, and the presenting symptoms of neuroblastoma are reviewed. The radiological findings of this neurogenic paediatric tumour are discussed.

Estridor inspiratorio en neonato por neuroblastoma cervical. Descripción de un caso

“…Sin embargo, hay otros tumores que dan un patrón similar en la RM, como es el caso de malformaciones linfáticas. Los linfangiomas no complicados habitualmente aparecen con señal hipointensa en T1 y marcada hiperintensidad en T2, que puede variar dependiendo del contenido en proteínas y la presencia de productos sanguíneos [5][6][7].…”

Neuroblastoma: Incidental Craniocerebral Metastasis - A Case Report

“…[8] The median age at diagnosis is 22 months. [9] Symptoms caused by skeletal metastases lead to bony pain and orbital wall metastases presenting as Panda sign or Raccoon eyes (due to orbital ecchymoses causing darkening of periorbital tissues) [9]. On CT, the tumour typically is heterogeneous with calcifications seen in 80-90% of cases [5].CNS metastasis in cases of primary adrenal neuroblastoma clinically occult in most of the cases and symptoms of visual disturbances and headaches often go unnoticed in very young children.…”

Pediatric primary and metastatic neuroblastoma: MRI findings

“…NBL arises from neural crest precursor cells of the sympathetic nervous system. In approximately 70% of cases, the primary NBL is located in the abdomen either in the adrenal medulla or in the retroperitoneum [5]. NBL can also develop anywhere along the sympathetic nervous system chain from the neck to the pelvis [5].…”