Neurobiology: Venom of Wasps and Initiation of Movements

Zill, Sasha N.; Keller, Bridget R.

doi:10.1016/j.cub.2008.04.045

Cited by 1 publication

(1 citation statement)

References 12 publications

(2 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Life-threatening multi-organ injuries following wasp and Asian giant hornet stings have been reported from time to time, but it is very unusual that so many people were killed and injured by Asian giant hornet in a short period of time. The wasp stings can directly cause toxin-induced acute renal failure because its venom contains histamine, melittin, apamin, phospholipases A1, hyaluronidase, acid phosphatase, and degranulating peptide mastoparan [ 4 , 5 ]. As one of these injured people, our patient had an anaphylaxis-like reaction, which seemed to be caused by a delayed hypersensitive reaction to the venom because his condition was improved by kidney-supportive measures along with oral methylprednisolone therapy and he clinically lacked wheal and respiratory symptoms.…”

Section: Discussionmentioning

confidence: 99%

Acute Interstitial Nephritis Following Multiple Asian Giant Hornet Stings

Liu

Zhai

et al. 2015

Am J Case Rep

View full text Add to dashboard Cite

Patient: Male, 42Final Diagnosis: Acute interstitial nephritisSymptoms: Difficulty breathing • headache • numbness • oliguriaMedication: MethylprednisoloneClinical Procedure: Plasma exchangeSpecialty: NephrologyObjective:Rare diseaseBackground:The Asian giant hornet is the largest wasp species in the world. Its stings can cause acute interstitial nephritis and acute renal failure. From July to October, 2013, Asian giant hornet attacks have killed 42 people and injured 1675 people with their powerful venomous stings in Hanzhong, Ankang, and Shangluo, three cities in the southern part of Shaanxi Province, China.Case Report:We report here a case of a 42-year-old man with acute interstitial nephritis following multiple Asian giant hornet stings. On admission, the patient had difficulty breathing, headache, and numbness in both limbs (arm and leg). He was treated in the Emergency Department and Department of Nephrology with plasma exchange and dialysis within 24 hours after being stung. A kidney biopsy revealed acute interstitial nephritis with interstitial infiltrations of eosinophils and lymphocytes. After intensive treatment, his liver function recovered within 10 days. Along with oral methylprednisolone, his renal function recovered 1 month later.Conclusions:This case shows that acute interstitial nephritis happens several days after being stung. Since the number of deaths in southern Shaanxi province is much higher than other places, our report draws the attention of fellow clinicians to the acute interstitial nephritis following multiple Asian giant hornet stings.

show abstract

Section: Discussionmentioning

confidence: 99%