Neurobiologie posttraumatischer und somatoformer Störungen im Alter

Abstract

Neurobiological data on posttraumatic disorders and somatoform disorders are diverse and not uniform. This is even more true when it comes to those disorders that are within the intersection of these two entities and, above all, their special features in the elderly. Psychophysiological, neuroanatomical, endocrine-immunological, genetic, and epigenetic factors play an important role here. With regard to posttraumatic stress disorder, for example, higher autonomic reactivity was observed, which indicates an acquired general sensitization of the nervous system.

Depression in old age, part 1

“…pathogenetischen Faktoren reicht von Genvarianten des "brainderived neurotrophic factor" (BDNF; [22]) bis zu den Spätfolgen psychischer Traumatisierungen [23]. pathogenetischen Faktoren reicht von Genvarianten des "brainderived neurotrophic factor" (BDNF; [22]) bis zu den Spätfolgen psychischer Traumatisierungen [23].…”

Stress: the good, the bad and the ugly?

“…As the results regarding both these facts are inconsistent, the main message of this paper is that older adults react to multiple stressors in a more adaptive way than younger adults. The capacity in highly vulnerable elderly people exposed to posttraumatic stress depends of many factors [12]. It is fascinating that it was now shown that psychotherapeutic interventions in posttraumatic stress disorder patients may reduce the amount of basal DNA breakage [13].…”