Neurobiological mechanisms of exercise and psychotherapy in depression: The SPeED study—Rationale, design, and methodological issues

Heinzel, Stephan; Rapp, Michael A.; Fydrich, Thomas; Ströhle, Andreas; Terán, Christina; Kallies, Gunnar; Schwefel, Melanie; Heißel, Andreas

doi:10.1177/1740774517729161

Cited by 24 publications

(13 citation statements)

References 127 publications

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“…These and other physiological changes are linked to prefrontal brain activation correlated with memory and cognitive control tasks. Moreover, neuroimaging research suggests that PE can indeed improve memory performance and cognitive control (Heinzel et al, 2018).…”

Section: Sports and Cognitive Abilities Trainingmentioning

confidence: 99%

How to Train Your Health: Sports as a Resource to Improve Cognitive Abilities in Cancer Patients

et al. 2019

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From a cognitive-psychological perspective, physical exercise (PE) and sports are an interesting tool for improving people’s cognitive abilities. One field of application for such a tool is decision making (DM) support in chronic patients, cancer patients, and survivors in particular. On the one hand, cancer patients and survivors have to continually take important decisions about their own care (e.g., treatment choice; changes in lifestyle), in collaboration with caregivers and health providers; on the other hand, side effects of treatment may be detrimental to cognitive abilities, such as attention, which make the health DM tasks even more demanding, complex, and emotionally disruptive for patients. Since cancer patients have to engage in healthy activities both for improving their own quality of life and for sustaining the effects of medications, clinical advice to engage in sport and PE is becoming more and more widespread within interventions. However, while sports are usually seen as healthy physical activities, their impact on cognitive abilities is mostly overlooked in the literature. The hypothesis of the present work is that sports could be fully exploited in their potential as focused exercises for cognitive ability training, in the field of cognitive training for chronic patients specifically. Indeed, literature shows that different sports (e.g., individual or team-based) influence and possibly augment cognitive abilities such as focused and divided attention, working memory, and DM under time constraints. Moreover, besides providing training for cognitive abilities, the experience of sports may represent an opportunity to explore, train and sharpen DM abilities directly: we identify five ways in which sport experiences may influence DM processes, and provide indications for future research on the topic.

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Section: Sports and Cognitive Abilities Trainingmentioning

confidence: 99%

How to Train Your Health: Sports as a Resource to Improve Cognitive Abilities in Cancer Patients

et al. 2019

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“…Previous studies explain this positive outcome of exercise in depression levels due to physiological and neurobiological mechanisms (46). Briefly, Heinzel et al (46) reported that aerobic training improves cardiorespiratory fitness, which stimulates neurotrophins (47, 48), stress-associated hormone cortisol (49), the oxygen and energy supply of the brain (50, 51), and the synthesis and release of endocannabinoids (central and peripheral). These changes might inhibit the hypothalamic–pituitary–adrenal axis, leading to a reduction in cortisol release (52) and, consequently, of the psychological stress response (53, 54), and positive affect (55).…”

Section: Discussionmentioning

confidence: 74%

Interval Training Improves Depressive Symptoms But Not Anxious Symptoms in Healthy Women

et al. 2019

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Background: Despite important advances in the relationship between exercise and mood disorders, especially regarding moderate-intensity continuous training, there is a lack of information about the chronic effects of interval training protocols. We compared the effects of two different interval training protocols [sprint interval training (SIT) and high-intensity interval training (HIIT)] on depressive and anxious symptoms in healthy women. Methods: Thirty-six women were randomly allocated to HIIT (n = 18) or SIT (n = 18) groups and performed 24 training sessions over 8 weeks (thrice a week). Levels of state–trait anxiety and depressive symptoms were evaluated using State–Trait Anxiety Inventory and Beck Depression Inventory, respectively, before and after training intervention. Results: Two-way analysis of variance (ANOVA) did not reveal a significant effect of time (p > 0.05), group intervention (p > 0.05), or time × group interaction (p > 0.05) on state–trait anxiety; however, two-way ANOVA showed a significant effect of time on depressive symptoms (p = 0.025) but not group effect (p = 0.548) or time × group interaction (p = 0.373). Depressive symptoms of the participants in both HIIT and SIT groups were reduced from baseline, (ΔHIIT) −17.5 ± 27.9% and (ΔSIT) −28.6 ± 47.5%, respectively. Conclusion: HIIT and SIT groups similarly improved depressive symptoms but not anxiety levels in healthy and physically active young adult women.

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“…This suggests that combined psychotherapy and exercise programs may have potential utility in helping cancer patients both physically and emotionally recover from their cancer experience. However, the evidence base for such combined lifestyle interventions is still very much in their infancy; thus highlighting the need for future research to test whether such combined psychotherapy and exercise interventions (eg, 25 ) may have synergist psychological and physical health benefits for distressed individuals recovering from cancer and other comorbid physical conditions.…”

Section: Discussionmentioning

confidence: 99%

Mental health literacy, treatment preferences and the lived experience of mental health problems in an Australian cancer sample

Kangas

Heißel

2020

Psycho-Oncology

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Objectives: The prevalence rates for mental health (MH) problems in cancer patients is high, although reduced uptake of services may be influenced by mental health literacy (MHL). The objective of this study was to investigate the MHL for depression and panic disorder (PD), including treatment preferences in Australian adults who had been diagnosed and treated for cancer, and whether MHL and treatment preferences was influenced by sex, age, and individuals' lived MH experience. Method: A total of 421 cancer survivors (n = 378 females) completed a self-report survey. Participants were asked to specify whether they had a lived experience with anxiety and/or depression, and to indicate treatment preferences for managing cancer-related distress. Two vignettes were administered to assess MHL for depression and PD. Results: The MHL accuracy for depression was higher than PD. Accuracy rates were higher for females with a lived experience with anxiety and/or depression; although the accuracy rate for PD was significantly lower in males. A high proportion of individuals preferred exercise and in-person counselling to manage depression and PD. Internet-based therapies were not strongly preferred for managing MH problems. Conclusions: The MHL for depression and PD is moderate for adult cancer survivors, with higher levels indicated for individuals with a personal lived experience with anxiety and/or depression. Public health campaigns for enhancing MHL should broaden to include individuals experiencing comorbid physical health conditions. Health providers also need to take into account client preferences for evidence-based therapies.

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Neurobiological mechanisms of exercise and psychotherapy in depression: The SPeED study—Rationale, design, and methodological issues

Cited by 24 publications

References 127 publications

How to Train Your Health: Sports as a Resource to Improve Cognitive Abilities in Cancer Patients

How to Train Your Health: Sports as a Resource to Improve Cognitive Abilities in Cancer Patients

Interval Training Improves Depressive Symptoms But Not Anxious Symptoms in Healthy Women

Mental health literacy, treatment preferences and the lived experience of mental health problems in an Australian cancer sample

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