Neurobiological mechanisms and therapeutic impact of electroconvulsive therapy (ECT)
Ana-Maria Cojocaru,
Antonia Ioana Vasile,
Simona Corina Trifu
Abstract:Electroconvulsive therapy (ECT) is an efficient therapeutic resource for psycho-pharmacotherapeutic resistant forms of depression. ECT is a form of electrical brain stimulation involving the induction of a controlled seizure, clinically similar to an epileptic seizure, that is initiated in the prefrontal region of the brain and spreads to the cortex and subcortex, including the diencephalic structures. This is achieved by creating a transcranial electric field and synchronously depolarizing neuronal membranes.… Show more
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