Neurobehavioral Changes of Shipyard Painters Exposed to Mixed Organic Solvents

Lee, Choong Ryeol; Jeong, Kyoung Sook; Kim, Yangho; Yoo, Changhee; Lee, Ji Ho; Choi, Young Hee

doi:10.2486/indhealth.43.320

Cited by 22 publications

(18 citation statements)

References 31 publications

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“…This is in concomitant with Crofton et al 1994, who stated that dizziness is an early symptoms due to solvents exposure. Our results are in agreement with Lee et al 2005, who reported that impaired memory, concentration levels and emotional disturbance were the complaints among shipyard painters workers occupationally exposed to toluene.…”

Section: Discussionsupporting

confidence: 93%

Dynamic Posturography Findings in Workers Exposed to Toluene

et al. 2010

Egypt. J. Occup. Med.

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Background Exposure to volatile organic solvents as toluene, in the workplace, is associated with deleterious effects involved in postural regulation. Objectives: The aim of this study is to detect the disturbances of the vestibular system due to exposure to toluene using dynamic posturography, putting a hypothesis to use dynamic posturography as a possible tool to identify the effects on balance among workers exposed to toluene. Subjects and methods: the study was performed on 30 workers exposed to toluene and 30 workers non exposed (control). History, dynamic posturography (the central integration of the vestibular, visual, and somatosensory inflow is evaluated using sensoriorganization test (SOT)) and hippuric acid measurement in urine were performed to both groups. Results: hippuric acid levels in urine were statistically significant higher among exposed workers when compared to the control. Dynamic posturography results were statistically significant lower in the exposed group in conditions SOT 3 (p=0.015), SOT 4 (p=0.014), SOT 5, (p=0.001) SOT 6 (p= 0.000) and CS (P =0.000) when compared to control group. A statistically significant negative correlation between urinary hippuric acid and dynamic posturography. There were significant negative correlation between duration of exposure to toluene and dynamic posturography. Conclusion: Exposure to toluene affects vestibular system so dynamic posturography is useful in balance assessment in workers exposed to toluene.

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Section: Discussionsupporting

confidence: 93%

Dynamic Posturography Findings in Workers Exposed to Toluene

et al. 2010

Egypt. J. Occup. Med.

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“…Early studies in Scandinavia suggested that long term, high level, solvent exposure might be associated with a syndrome of personality change, memory impairment, and neurological deficits variously termed chronic toxic encephalopathy (CTE), the psycho-organic syndrome or solvent neurotoxicity [3] The prevalence of individual psychological symptoms were found to be significantly higher among paint manufacturing workers for every question. These results are consistent with the previous studies conducted on spray painters exposed to a mixture of volatile organic solvents and noticed neurobehavioral changes in their neurobehavioral profile [9,10]. From these results, we can conclude that because there are more than nine million workers exposed to solvents in the workplace [11], this population is at risk for a high prevalence of psychiatric problems and the potential for Table 5.…”

Section: Discussionsupporting

confidence: 91%

Health Hazards of Solvents Exposure among Workers in Paint Industry

Hassan¹,

Elnagar²,

Tayeb³

et al. 2013

OJSST

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Background: Paints and coatings include paints, varnishes, lacquers, stains, printing inks and more. A wide variety of volatile solvents are used in paint and coating manufacturing including aliphatic and aromatic hydrocarbons, alcohols, ketones and consist of more than 30% of most of paints. At low or moderate concentrations, the organic solvents may cause transient symptoms such as euphoria, headache and dizziness. At high concentrations, anaesthesia and disturbances in respiration and circulation may occur and may lead to death. Long-term exposure may cause damage to the Central Nervous System (CNS), such as cognitive and emotional deficits. Methods: A cross sectional study was conducted among 92 male workers exposed to organic solvents on performing their job in Koratol Paint Factory in Alaama Village in Sharkia Governorate. Another group of 95 workers, not working with organic solvents were selected from the Faculty of Medicine in Zagazig University and considered as a control group. All participants in the study were subjected to a pre-designed questionnaire to collect information about personal, socio-demographic data, occupational history, use of personal protective equipments, frequently perceived health complaints which included irritation symptoms (skin, eye and nose) and Questions of the validated questionnaire for the neuropsychological symptoms (Q22). Results: The neuropsychological symptoms score (Q22) revealed that 63.04% of solvents exposed paint manufacturing workers had neuropsychological symptoms, compared to about only 2.1% in control group and the difference was statistically significant. Regarding the relation between types of job done and results of neuropsychological symptoms score (Q22) there was increased risk for neuropsychological symptoms in production group than packing group (OR = 13.94) and for the duration of work the risk increased in workers with duration over 15 years (OR = 32.84). Logistic regression analysis showed that the most important predictors of neuropsychological symptoms were the type of job performed by the workers such as production or packing and their duration of work ≥15 years. Conclusions: The paint industry workers were at increased risk of several irritant and neuropsychological symptoms which significantly related to exposure to paint and organic solvents.

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“…(7–10,13,15,26,36) Several studies conducted industrial hygiene measurements to be combined with JEMs for deriving a lifetime exposure index. (8–9,13,36) However, historical trends of solvent air concentration were not considered in those studies. Kishi et al (15) have incorporated the historical changes of solvent air concentrations for estimating solvent exposure indices, but protective equipment use was not considered.…”

Section: Discussionmentioning

confidence: 99%

“…A cumulative lifetime exposure index can be derived by combining chemical measurements and JEMs and has been used in several previous studies of painters and workers at paint manufacturing companies. (7–9) …”

Section: Introductionmentioning

confidence: 99%

Development of Solvent Exposure Index for Construction Painters

Wang¹,

Qian²,

Weisel³

et al. 2011

Journal of Occupational and Environmental Hygiene

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This article describes methodological approaches for reconstructing long-term occupational exposure to organic solvents among construction painters. A detailed exposure questionnaire was administered to 125 painters to develop a job exposure matrix (JEM). The questionnaire inquired about painting activities with solvent-based paints and use of protection equipment for the previous 25 years in 5-year intervals. Current and historical distributions of solvent air concentrations were assessed for the same time period based on the following information: industrial hygiene measurements, paint composition changes, and VOC emission rate changes from architectural and industrial maintenance coatings. Changes in protection factors of respirators were also assessed. A cumulative solvent exposure index was calculated for each painter through Monte Carlo simulations by combining appropriate input distributions of solvent air concentrations and protection factors of respirators with JEM. Sensitivity simulations revealed that the historical variations in solvent air concentrations had a higher impact on the cumulative solvent exposure index than changes in protection factors for respirators. Fifty-eight percent of painters were classified with a different exposure quartile when the solvent exposure index was used vs. an exposure based only on years using solvent-based paints, suggesting the need for more detailed exposure analysis than just years working when conducting epidemiologic studies for this worker population.

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Neurobehavioral Changes of Shipyard Painters Exposed to Mixed Organic Solvents

Cited by 22 publications

References 31 publications

Dynamic Posturography Findings in Workers Exposed to Toluene

Dynamic Posturography Findings in Workers Exposed to Toluene

Health Hazards of Solvents Exposure among Workers in Paint Industry

Development of Solvent Exposure Index for Construction Painters

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