Neuro-otologic manifestations of tuberculosis. “The great imitator"

Rubio, Johanna Miguelina Diplan; Alarcón, Alfredo Vega; Díaz, Marité Palma; Vales, Olivia; Hinojosa, Ramón; Angel, Josefina Morales del; Romero, Dina; Sánchez, Yolanda Guerrero

doi:10.1016/j.amjoto.2015.01.018

Cited by 10 publications

(6 citation statements)

References 12 publications

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“…Los signos y síntomas incluyen la otorrea, hipoacusia, tinnitus, perforaciones del tímpano, tejido de granulación, presencia de pólipos en el conducto auditivo externo, otalgia y paresia o parálisis del nervio facial 4 . La otorrea es el signo más frecuentemente reportado, siendo refractaria a los tratamientos antibióticos típicos, seguido de hipoacusia y otalgia 5,7,8 . Los pacientes pueden igualmente presentar con vértigo y desequilibrio 6,8 .…”

Section: Discussionunclassified

“…La otorrea es el signo más frecuentemente reportado, siendo refractaria a los tratamientos antibióticos típicos, seguido de hipoacusia y otalgia 5,7,8 . Los pacientes pueden igualmente presentar con vértigo y desequilibrio 6,8 . A la otomicroscopía, se observan comúnmente perforaciones del tímpano, que pueden ser única o múltiples; sin embargo, se puede igualmente observar una membrana timpánica íntegra.…”

Section: Discussionunclassified

“…A la otomicroscopía, se observan comúnmente perforaciones del tímpano, que pueden ser única o múltiples; sin embargo, se puede igualmente observar una membrana timpánica íntegra. Se pueden encontrar pólipos y tejido de granulación en el conducto auditivo externo, otitis media con efusión o retracciones de la membrana timpánica 5,[7][8][9] . Los pacientes pueden desarrollar hipoacusia neurosensorial, conductiva o mixta.…”

Section: Discussionunclassified

“…Los pacientes pueden desarrollar hipoacusia neurosensorial, conductiva o mixta. El compromiso del nervio facial es raro, y se ha observado en 9% a 33% de los casos 6,8,10 . Este es más frecuente en la otomastoiditis tuberculosa, al comparar la incidencia con casos de otitis media crónica no tuberculosa, especialmente en ausencia de colesteatoma 10 .…”

Section: Discussionunclassified

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Otomastoiditis por Mycobacterium tuberculosis: Un diagnóstico desafiante

et al. 2019

Rev. Otorrinolaringol. Cir. Cabeza Cuello

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Section: Discussionunclassified

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Otomastoiditis por Mycobacterium tuberculosis: Un diagnóstico desafiante

et al. 2019

Rev. Otorrinolaringol. Cir. Cabeza Cuello

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“…Cranial nerves II, III, IV, VI, and XII are the most frequently affected nerves 4,9,64 (Figure 5). In most cases, multiple cranial nerves are involved 63 .…”

Section: Specific Issues When Diagnosing Cns Tb and The Role Of Mrimentioning

confidence: 99%

Pediatric and adult meningeal, parenchymal, and spinal tuberculosis: A neuroimaging review

Mertiri,

Freiling,

Desai

et al. 2023

Journal of Neuroimaging

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Neurotuberculosis is defined as a tuberculous infection of the meninges, brain parenchyma, vessels, cranial and spinal nerves, spinal cord, skull, and spine that can occur either in a localized or in a diffuse form.It is a heterogeneous disease characterized by many imaging appearances and it has been defined as “the great mimicker” due to similarities with many other conditions.The diagnosis of central nervous system (CNS) tuberculosis (TB) is based on clinical presentation, neuroimaging findings, laboratory and microbiological findings, and comprehensive evaluation of the response to anti‐TB drug treatment.However, the absence of specific symptoms, the wide spectrum of neurological manifestations, the myriad of imaging findings, possible inconclusive laboratory results, and the paradoxical reaction to treatment make the diagnosis often challenging and difficult, potentially delaying adequate treatment with possible devastating short‐term and long‐term neurologic sequelae.Familiarity with the imaging characteristics helps in accurate diagnosis and may prevent or limit significantly morbidity and mortality. The goal of this review is to provide a comprehensive up‐to‐date overview of the conventional and advanced imaging features of CNS TB for radiologists, neuroradiologists, and pediatric radiologists. We discuss the most typical neurotuberculosis imaging findings and their differential diagnosis in children and adults with the goal to provide a global overview of this entity.

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