Neuro-ophthalmologic complications of coronavirus disease 2019 (COVID-19)

Optic Neuritis in a Patient with Seropositive Myelin Oligodendrocyte Glycoprotein Antibody During the Post-COVID-19 Period

“…[20][21][22][23] Our patient is not the only one who demonstrated a connection between SARS-CoV-2 and MOG antibodies in the context of optic neuritis. [5][6][7][8] Reports are scarce, which is understandable in the pandemic situation. Nevertheless, they are sufficient to be informative.…”

“…Neuro-ophthalmological manifestations are rare in COVID-19. 1,[5][6][7][8][9] Three reports identified connections between SARS-CoV-2 and optic neuritis, with or without spinal or cerebral demyelinating lesions, associated with serum antibodies against myelin oligodendrocyte glycoprotein (MOG). [6][7][8] Two cases appeared during symptomatic COVID-19, and one appeared a few weeks after the disease.…”

Internuclear ophthalmoplegia as a presenting feature in a COVID-19-positive patient

“…12 Reports of neuro-ophthalmic findings such as cranial nerve paresis, optic neuritis, gaze palsy, vision loss and so on are being increasingly described in the literature. [6][7][8][9][10][11][12][13][14][15][16] Multiple mechanisms in the aetiopathogenesis of neuroophthalmic manifestations in COVID-19 have been proposed, and these include postviral inflammatory syndrome, sequelae of a proinflammatory state and as a consequence of systemic conditions, such as cardiovascular disease or uncontrolled hypertension. 14 Haematological spread and direct viral invasion have also been suggested.…”

“…[6][7][8][9][10][11][12][13][14][15][16] Multiple mechanisms in the aetiopathogenesis of neuroophthalmic manifestations in COVID-19 have been proposed, and these include postviral inflammatory syndrome, sequelae of a proinflammatory state and as a consequence of systemic conditions, such as cardiovascular disease or uncontrolled hypertension. 14 Haematological spread and direct viral invasion have also been suggested. 12 Cases of oculomotor nerve palsy, 13 Miller Fisher syndrome, 6 abducens nerve palsy 7 8 and tonic pupil 15 have been reported earlier, which resolved with treatment.…”

Neurite óptica isquêmica não arterítica como complicação da COVID-19: Um relato de caso / Non-arteritic ischemic optic neuritis as a complication of COVID-19: A case report

“…O Coronavírus 2 da Síndrome Respiratória Aguda Severa (SARS-CoV-2) é um vírus RNA encapsulado responsável por mais de 2,4 milhões de mortes em todo o mundo até o momento. Trata-se de um vírus que invade as células hospedeiras ligando-se aos receptores da enzima conversora de angiotensina 2 (ECA2), cuja presença já foi confirmada na conjuntiva, coroide, endotélio vascular e nervos do organismo humano 1,2 .…”