Neuro-Ophthalmic and Clinical Characteristics of Brain Tumors in Children in Macau

Ng, In Sim; Marques, Jorge Sales; Hei, Ao

doi:10.31080/aspe.2019.02.0179

Cited by 1 publication

(2 citation statements)

References 7 publications

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“…The other neurological signs and symptoms seen in our study were cerebellar signs (45.7%), optic nerve involvement (82.9%), other types of cranial nerve involvement (42.8%), seizures (40%), altered sensorium (14.3%), ataxia (11.4%), motor deficits (8.6%), endocrine involvement (5.7%), and increased head circumference (2.9%). These are consistent with various similar studies in the literature on pediatric intracranial tumours [ 2 , 3 , 11 , 12 ].…”

Section: Discussionsupporting

confidence: 93%

“…This is due to a higher incidence of meningiomas and pituitary adenomas in females among adult patients. In contrast to this observation, the literature on pediatric brain tumours suggests a higher incidence of intracranial tumours in boys similar to our study [ 11 , 12 ]. In developing countries, this may also be a reflection of the prevalent gender bias of the relatives seeking treatment.…”

Section: Discussionsupporting

confidence: 68%

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Neuroophthalmic Manifestations of Intracranial Tumours in Children

Kotecha

Gotecha

Chugh

et al. 2021

Case Reports in Ophthalmological Medicine

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Background. All children between 0 and 16 years presenting with brain tumours confirmed by Magnetic Resonance Imaging (MRI) and treated surgically in our institute were included in this study. Objective. The aim of this study is to evaluate the neuroophthalmic and clinical characteristics of intracranial space occupying lesions in children. Methods. Neuroophthalmic manifestations along with location of the tumour by contrast-enhanced MRI, type of surgical intervention, and postoperative histopathological diagnosis were evaluated. Results. In pediatric brain tumours, male preponderance was seen and supratentorial location was more common in general, while in older children, infratentorial tumours were more common than supratentorial tumours. Headache, vomiting, and cerebellar signs were the commonest neurological features. Diminution of vision, diplopia, and strabismus were the commonest ophthalmic symptoms. Papilledema, ophthalmoparesis, and nystagmus were the most frequent ophthalmological signs. Neurological manifestations of seizures, altered sensorium and motor deficits were more frequently seen in supratentorial tumours, while cranial nerve involvement and ataxia were seen in infratentorial tumours. Ophthalmological manifestations including diplopia, strabismus, ophthalmoparesis, and nystagmus were more frequently seen in infratentorial tumours. Astrocytoma was the most frequent histopathological diagnosis followed by medulloblastoma. Conclusion. Diagnosis of pediatric intracranial tumours is complex and requires a multidisciplinary approach for prompt management. An ophthalmologist should have a high index of suspicion for brain tumours especially in patients presenting with common ocular symptoms like diminution of vision, diplopia, and strabismus without any neurological symptoms.

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