Neurexins control the strength and precise timing of glycinergic inhibition in the auditory brainstem
He-Hai Jiang,
Ruoxuan Xu,
Xiupeng Nie
et al.
Abstract:Neurexins play diverse functions as presynaptic organizers in various glutamatergic and GABAergic synapses. However, it remains unknown whether and how neurexins are involved in shaping functional properties of the glycinergic synapses, which mediate prominent inhibition in the brainstem and spinal cord. To address these issues, we examined the role of neurexins in a model glycinergic synapse between the principal neuron in the medial nucleus of the trapezoid body (MNTB) and the principal neuron in the lateral… Show more
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