Abstract:Malignant brain tumors are nearly untreatable due to their highly infi ltrative nature and resistance to existing therapies. The main reason for recurrent tumor growth is believed to be the presence of tumor cells that migrate great distances into the brain tissue. In addition, poor delivery of therapeutics to the tumors due to blood-brain barrier limits the clinical success of currently available systemically delivered antitumor therapies. Recently, a different mode of therapeutic delivery, whereby therapeuti… Show more
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