Abstract:Neural stem cells (NSCs) present attractive natural drug
delivery
systems (DDSs). Their migratory potential enables crossing of the
blood–brain barrier and efficient and selective accumulation
near malignant cells. Here, we present the potential of NSCs as DDSs
for nucleoside analogue-conjugated nanogels (NGs). Two different approaches
were investigated: the intracellular loading and extracellular cell
surface decoration with NGs. For both designs, the tumor-specific
migratory potentials of NSCs remained uncha… Show more
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