Neural responses to pup calls and pup odors in California mouse fathers and virgin males

Wilson, Kerianne M.; Arquilla, April M.; Rosales-Torres, Kelsey M.; Hussein, Marwa M.; Chan, May G.; Razak, Khaleel A.; Saltzman, Wendy

doi:10.1016/j.bbr.2022.114024

Cited by 5 publications

(4 citation statements)

References 86 publications

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“…We 71 recently found that, in male California mice (fathers and virgins), c‐Fos expression in the MPOA was significantly higher following exposure to pup odours, either alone or in combination with pre‐recorded pup vocalizations, than after exposure to control stimuli. Moreover, MPOA c‐Fos levels following exposure to pre‐recorded pup vocalizations were increased by simultaneous exposure to pup odours 71 …”

Section: Plasticity In Multisensory Integrationmentioning

confidence: 99%

“…For example, male prairie voles cohabitating with a female for 2 weeks had higher expression of c‐Fos, the protein product of the immediate early gene c‐fos , in their ventral tegmental area after exposure to pup odour, compared to males housed with other males 99 . In California mice, fathers had lower expression of c‐Fos in the MOB compared to virgins, independent of acute exposure to pup odours 71 …”

Section: Plasticity In the Olfactory Systemsmentioning

confidence: 99%

“…99 In California mice, fathers had lower expression of c-Fos in the MOB compared to virgins, independent of acute exposure to pup odours. 71 Changes in the perception of pup odours by fathers are likely mediated by cell proliferation in the SVZ and subsequent migration of new cells to the olfactory bulb that occur during the transition to fatherhood. 72 Male C57BL/6 mice housed with their mate beyond the birth of their first litter had greater SVZ cell proliferation 2 days postpartum compared to males removed from their mate and pups shortly after parturition.…”

Section: Plasticity In the Olfactory Pathways In Fathersmentioning

confidence: 99%

“…Moreover, MPOA c-Fos levels following exposure to pre-recorded pup vocalizations were increased by simultaneous exposure to pup odours. 71 In an elegant series of studies, Cohen and colleagues 118,197 identified effects of pup odours on neurones in the primary auditory cortex of lactating C57BL/6 mice. Both spontaneous and tone-evoked electrophysiological activity of individual neurones were altered by simultaneous exposure to pup odours, with most neurones showing a transient increase or a decrease in firing rates.…”

Section: Neural Basis and Plasticity Of Multisensory Integration In P...mentioning

confidence: 99%

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The parental umwelt: Effects of parenthood on sensory processing in rodents

Wilson

Arquilla

Saltzman

2023

J Neuroendocrinology

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An animal's umwelt, comprising its perception of the sensory environment, which is inherently subjective, can change across the lifespan in accordance with major life events. In mammals, the onset of motherhood, in particular, is associated with a neural and sensory plasticity that alters a mother's detection and use of sensory information such as infant‐related sensory stimuli. Although the literature surrounding mammalian mothers is well established, very few studies have addressed the effects of parenthood on sensory plasticity in mammalian fathers. In this review, we summarize the major findings on the effects of parenthood on behavioural and neural responses to sensory stimuli from pups in rodent mothers, with a focus on the olfactory, auditory, and somatosensory systems, as well as multisensory integration. We also review the available literature on sensory plasticity in rodent fathers. Finally, we discuss the importance of sensory plasticity for effective parental care, hormonal modulation of plasticity, and an exploration of temporal, ecological, and life‐history considerations of sensory plasticity associated with parenthood. The changes in processing and/or perception of sensory stimuli associated with the onset of parental care may have both transient and long‐lasting effects on parental behaviour and cognition in both mothers and fathers; as such, several promising areas of study, such as on the molecular/genetic, neurochemical, and experiential underpinnings of parenthood‐related sensory plasticity, as well as determinants of interspecific variation, remain potential avenues for further exploration.

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Section: Plasticity In Multisensory Integrationmentioning

confidence: 99%

Section: Plasticity In the Olfactory Systemsmentioning

confidence: 99%