Neural representation of interaural correlation in human auditory brainstem: Comparisons between temporal-fine structure and envelope

Wang, Qian; Lu, Hao; Wu, Zhemeng; Li, Liang

doi:10.1016/j.heares.2018.05.015

Cited by 11 publications

(9 citation statements)

References 62 publications

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“…In the present study, older adult participants with PC exhibited a higher PTA threshold, which is related to hair cell dysfunction, than their age-control participants without PC. The results of the present study also demonstrated that the PTA threshold was associated with the noise-induced changes in the TFS component of the FFRs, which reflect the brainstem representations of sound TFS signals in both humans (Wang et al, 2018) and rats (Wang and Li, 2015, 2017, 2018; Luo et al, 2017).…”

Section: Discussionsupporting

confidence: 73%

“…In the present study, we examined FFR under both quiet and noise conditions in older adults with and without PC who were native speakers of a tonal language (Mandarin) and analyzed the FFR results together with their pure tone audiometry (PTA) thresholds and SIN performance. We hypothesized that the loss of hearing sensitivity and the reduction in SIN perception of listeners with PC, particularly when listening under noise conditions, may be associated with the decline in the subcortical representations of the envelope and TFS signals, which can be measured in both humans (Wang et al, 2018) and laboratory animals (Wang and Li, 2015, 2017, 2018; Luo et al, 2017). The primary aim of the present study was to obtain a better understanding of the PC-related alterations in the neural representation of envelope and TFS cues.…”

Section: Introductionmentioning

confidence: 99%

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Effects of Phase-Locking Deficits on Speech Recognition in Older Adults With Presbycusis

Hao

Wang

et al. 2018

Front. Aging Neurosci.

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Objective: People with presbycusis (PC) often report difficulties in speech recognition, especially under noisy listening conditions. Investigating the PC-related changes in central representations of envelope signals and temporal fine structure (TFS) signals of speech sounds is critical for understanding the mechanism underlying the PC-related deficit in speech recognition. Frequency-following responses (FFRs) to speech stimulation can be used to examine the subcortical encoding of both envelope and TFS speech signals. This study compared FFRs to speech signals between listeners with PC and those with clinically normal hearing (NH) under either quiet or noise-masking conditions.Methods: FFRs to a 170-ms speech syllable /da/ were recorded under either a quiet or noise-masking (with a signal-to-noise ratio (SNR) of 8 dB) condition in 14 older adults with PC and 13 age-matched adults with NH. The envelope (FFRENV) and TFS (FFRTFS) components of FFRs were analyzed separately by adding and subtracting the alternative polarity responses, respectively. Speech recognition in noise was evaluated in each participant.Results: In the quiet condition, compared with the NH group, the PC group exhibited smaller F0 and H3 amplitudes and decreased stimulus-response (S-R) correlation for FFRENV but not for FFRTFS. Both the H2 and H3 amplitudes and the S-R correlation of FFRENV significantly decreased in the noise condition compared with the quiet condition in the NH group but not in the PC group. Moreover, the degree of hearing loss was correlated with noise-induced changes in FFRTFS morphology. Furthermore, the speech-in-noise (SIN) threshold was negatively correlated with the noise-induced change in H2 (for FFRENV) and the S-R correlation for FFRENV in the quiet condition.Conclusion: Audibility affects the subcortical encoding of both envelope and TFS in PC patients. The impaired ability to adjust the balance between the envelope and TFS in the noise condition may be part of the mechanism underlying PC-related deficits in speech recognition in noise. FFRs can predict SIN perception performance.

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Section: Discussionsupporting

confidence: 73%

Section: Introductionmentioning

confidence: 99%

Effects of Phase-Locking Deficits on Speech Recognition in Older Adults With Presbycusis

Hao

Wang

et al. 2018

Front. Aging Neurosci.

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“…In contrast, if the sound waves at the left and right ears are independently generated, the interaural correlation is near to zero. The interaural correlation can be represented at both the neurophysiological level (Wang et al, 2018) and the perceptual level (Blauert and Lindemann, 1986). When sounds, i.e., arbitrary noises, arrive at the two ears simultaneously, identical sounds (interaural correlation = 1) at the two ears are perceptually fused into a single image at the center area of the head, while binaurally independent sounds are perceived as two separated sound images at each ear (Blauert and Lindemann, 1986).…”

Section: Introductionmentioning

confidence: 99%

Sensitivity to a Break in Interaural Correlation in Frequency-Gliding Noises

Fan

Kong

et al. 2021

Front. Psychol.

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This study was to investigate whether human listeners are able to detect a binaurally uncorrelated arbitrary-noise fragment embedded in binaurally identical arbitrary-noise markers [a break in correlation, break in interaural correlation (BIAC)] in either frequency-constant (frequency-steady) or frequency-varied (unidirectionally frequency gliding) noise. Ten participants with normal hearing were tested in Experiment 1 for up-gliding, down-gliding, and frequency-steady noises. Twenty-one participants with normal hearing were tested in Experiment 2a for both up-gliding and frequency-steady noises. Another nineteen participants with normal hearing were tested in Experiment 2b for both down-gliding and frequency-steady noises. Listeners were able to detect a BIAC in the frequency-steady noise (center frequency = 400 Hz) and two types of frequency-gliding noises (center frequency: between 100 and 1,600 Hz). The duration threshold for detecting the BIAC in frequency-gliding noises was significantly longer than that in the frequency-steady noise (Experiment 1), and the longest interaural delay at which a duration-fixed BIAC (200 ms) in frequency-gliding noises could be detected was significantly shorter than that in the frequency-steady noise (Experiment 2). Although human listeners can detect a BIAC in frequency-gliding noises, their sensitivity to a BIAC in frequency-gliding noises is much lower than that in frequency-steady noise.

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“…Human listeners with schizophrenia often find it difficult to recognize target speech in ‘cocktail party’ environments (Li et al, 2017; Wu et al, 2012; Wu, Li, et al, 2013; Wu, Wang, & Li, 2018; Wu, Zheng, et al, 2018; Wu, Zheng, Li, Wu, et al, 2017; Wu, Zheng, Li, Zhang, et al, 2017; Zheng et al, 2016, 2018). This schizophrenia‐associated difficulty may arise from the impaired precision of central representations of acoustic signals, including the impaired sensitivity to changes in interaural correlation, which underlies the ability to distinguish concurrent sounds, to localize sound sources, and to perceptually segregate the target sound from competing masking sounds (Goupell et al, 2018; Huang, Huang, et al, 2009; Li et al, 2013; Lotfi et al, 2019; Lüddemann et al, 2009; Ramage et al, 2012, 2016; Spencer et al, 2016; Wang et al, 2018; Weintraub et al, 2012). However, there have been no studies to examine whether schizophrenia affects the interaural correlation processing.…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, sensory memory is impaired in people with schizophrenia (Catts et al, 1995; Javitt et al, 1999; Todd et al, 2000), probably because of impaired processing precision in the auditory system (Bates, 2005; Javitt et al, 1997; March et al, 1999). Theoretically, without precise representations of acoustic signals (especially TFS information) from the two ears (Massaro, 1972), the central computation of interaural correlation is impossible, particularly when an interaural delay of some milliseconds is introduced (Moore, 2020; Wang et al, 2018). The faithful temporal storage of the acoustic signals has been termed primitive auditory memory (PAM) and recognized as an early stage in the chain of the transient auditory memory system (Huang, Huang, et al, 2009; Li et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Impaired interaural correlation processing in people with schizophrenia

Zheng

Liu

et al. 2021

Eur J of Neuroscience

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Detection of transient changes in interaural correlation is based on the temporal precision of the central representations of acoustic signals. Whether schizophrenia impairs the temporal precision in the interaural correlation process is not clear. In both participants with schizophrenia and matched healthy-control participants, this study examined the detection of a break in interaural correlation (BIC, a change in interaural correlation from 1 to 0 and back to 1), including the longest interaural delay at which a BIC was just audible, representing the temporal extent of the primitive auditory memory (PAM). Moreover, BIC-induced electroencephalograms (EEGs) and the relationships between the early binaural psychoacoustic processing and higher cognitive functions, which were assessed by the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), were examined. The results showed that compared to healthy controls, participants with schizophrenia exhibited poorer BIC detection, PAM and RBANS score. Both the BIC-detection accuracy and the PAM extent were correlated with the RBANS score. Moreover, participants with schizophrenia showed weaker BIC-induced N1-P2 amplitude which was correlated with both theta-band power and intertrial phase coherence. These results suggested that schizophrenia impairs the temporal precision of the central representations of acoustic signals, affecting both interaural correlation processing and higher-order cognitions.

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Neural representation of interaural correlation in human auditory brainstem: Comparisons between temporal-fine structure and envelope

Cited by 11 publications

References 62 publications

Effects of Phase-Locking Deficits on Speech Recognition in Older Adults With Presbycusis

Effects of Phase-Locking Deficits on Speech Recognition in Older Adults With Presbycusis

Sensitivity to a Break in Interaural Correlation in Frequency-Gliding Noises

Impaired interaural correlation processing in people with schizophrenia

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