Neural Mechanism for Spatial Memory Exposed to Mozart Music

Abstract

In order to further investigate the structural characteristics of some music tracks that may produce the "Mozart effect", this paper describes the key musical elements of "Mozart effect". Mozart K.448 and reversed Mozart K.448 are chosen as music stimulus materials to examine ethological changes of rodents and students. It has been proven that there is indeed the "Mozart effect". We also apply molecular biology techniques to carry out profound discussion on production mechanism of "Mozart effect". The results show that in hippocampus region, with the extension of music exposure time, the average optical density of the Mozart group is significantly higher than that of the blank group in appropriate development phase. The protein expression levels of BDNF/TrkB in the hippocampus and in auditory cortex regions of rats exposed to Mozart music in different development phases have been significantly increased, which coincides with ethological findings.

An analysis of the relationship of “the Mozart effect” with BDNF levels in anatomy education

“…Mozart K448 sonata played to mice increased spatial performance as well as increased BDNF and TrkB expression levels in newborn pups. 47 Of course, it is more possible to talk about these effects with greater certainty due to technical reasons in studies using animals. However, there is a lack of reflection on human cognitive skills in animal studies.…”

“…Finally, a study supporting the relationship between BDNF and the Mozart effect also provides an interesting result about how long the Mozart effect can last. Mozart K448 sonata played to mice increased spatial performance as well as increased BDNF and TrkB expression levels in newborn pups 47 . Of course, it is more possible to talk about these effects with greater certainty due to technical reasons in studies using animals.…”