“…Another gene family with some proneural-like activity is the Snail family; snail, (sna), escargot (esg) and worniou (wor), which act redundantly during CNS development (Ashraf et al, 1999;Ashraf and Ip, 2001;Cai et al, 2001). While, sna, esg, wor triple mutants do not show an apparent reduction in early NB numbers (Ashraf et al, 1999), wor mutants, also heterozygous for sna and esg, display a loss of NBs at later stages (Bahrampour et al, 2017). In addition, co-misexpression of a set of NB factors, which included Wor and SoxN, was shown to be sufficient for generating ectopic NBs broadly in the developing embryonic ectoderm, and even in developing wing discs (Bahrampour et al, 2017).…”