Neural interfaces: Bridging the brain to the world beyond healthcare

Abstract

Neural interfaces, emerging at the intersection of neurotechnology and urban planning, promise to transform how we interact with our surroundings and communicate. By recording and decoding neural signals, these interfaces facilitate direct connections between the brain and external devices, enabling seamless information exchange and shared experiences. Nevertheless, their development is challenged by complexities in materials science, electrochemistry, and algorithmic design. Electrophysiological crosstalk and the mismatch between electrode rigidity and tissue flexibility further complicate signal fidelity and biocompatibility. Recent closed‐loop brain‐computer interfaces, while promising for mood regulation and cognitive enhancement, are limited by decoding accuracy and the adaptability of user interfaces. This perspective outlines these challenges and discusses the progress in neural interfaces, contrasting non‐invasive and invasive approaches, and explores the dynamics between stimulation and direct interfacing. Emphasis is placed on applications beyond healthcare, highlighting the need for implantable interfaces with high‐resolution recording and stimulation capabilities.

Injectable Fluorescent Neural Interfaces for Cell-Specific Stimulating and Imaging

“…Deciphering the complex structure of the brain and understanding its intricate mechanisms of neuronal communication have been pivotal in scientific research. The urgency of this endeavor is highlighted by the widespread occurrence of neurodegenerative disorders such as epilepsy, Parkinson’s, and Alzheimer’s, − which impact millions worldwide.…”