Neural feedback is effective in preterm infants during neurally adjusted ventilatory assist, when using clinically relevant settings

Bridier, Armelle; François, Tine; Baudin, Florent

doi:10.1002/ppul.24478

Cited by 3 publications

(1 citation statement)

References 7 publications

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“…However, in this previous case report ( 12 ), the initial NAVA level was set at 3 cmH2O/µV, which is higher than in our study. A letter to the editor ( 22 ) highlighted the concern about setting the NAVA level above 2.5 cmH2O/µV, suggesting it might provide excessive assistance to premature infants and lead to lower Edi peak levels, as observed in the aforementioned case report.…”

Section: Discussionmentioning

confidence: 92%

Case Report: Neurally adjusted ventilatory assist as an effective rescue treatment for pulmonary interstitial emphysema in extremely low birth weight infants

Chen,

Chung,

Kang

et al. 2024

Front. Pediatr.

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Pulmonary interstitial emphysema (PIE) is a complication observed in extremely low birth weight (ELBW) infants on mechanical ventilation. Despite various proposed therapeutic interventions, the success rates have shown inconsistency. Neurally adjusted ventilatory assist (NAVA) stands out as a novel respiratory support mode, offering lower pressure and tidal volume in comparison to conventional ventilation methods. In this case report, we present five ELBW infants with refractory PIE who were transitioned to NAVA ventilation. Following the switch to NAVA, all cases of PIE gradually resolved. In contrast to traditional modes, NAVA provided respiratory support with significantly lower fraction of inspired oxygen, reduced peak inspiratory pressure, diminished mean airway pressure, and decreased tidal volume within 7 days of NAVA utilization (p = 0.042, 0.043, 0.043, and 0.042, respectively). Consequently, we propose that NAVA could serve as a valuable rescue treatment for ELBW infants with PIE.

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Section: Discussionmentioning

confidence: 92%