Neural effects of dopaminergic compounds revealed by multi-site electrophysiology and interpretable machine-learning
Sampath K. T. Kapanaiah,
Holger Rosenbrock,
Bastian Hengerer
et al.
Abstract:BackgroundNeuropsychopharmacological compounds may exert complex brain-wide effects due to an anatomically and genetically broad expression of their molecular targets and indirect effects via interconnected brain circuits. Electrophysiological measurements in multiple brain regions using electroencephalography (EEG) or local field potential (LFP) depth-electrodes may record fingerprints of such pharmacologically-induced changes in local activity and interregional connectivity (pEEG/pLFP). However, in order to … Show more
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