Neural Decoding and Feature Selection Techniques for Closed-Loop Control of Defensive Behavior
Jinhan Liu,
Rebecca Younk,
Lauren M Drahos
et al.
Abstract:ObjectiveMany psychiatric disorders involve excessive avoidant or defensive behavior, such as avoidance in anxiety and trauma disorders or defensive rituals in obsessive-compulsive disorders. Developing algorithms to predict these behaviors from local field potentials (LFPs) could serve as foundational technology for closed-loop control of such disorders. A significant challenge is identifying the LFP features that encode these defensive behaviors.ApproachWe analyzed LFP signals from the infralimbic cortex and… Show more
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