Neural correlates of psychological resilience and their relation to life satisfaction in a sample of healthy young adults

Kong, Feng; Wang, Xu; Hu, Siyuan; Liu, Jia

doi:10.1016/j.neuroimage.2015.08.020

Cited by 141 publications

(123 citation statements)

References 85 publications

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“…However, as Kong et al (2015d) mentioned, this study failed to find an association of resilience with other PFC regions such as OFC, which has been demonstrated in studies on disorders related to stress, as well as studies on healthy populations (Liberzon and Sripada, 2008; Reynaud et al , 2013; Sekiguchi et al , 2015). Because both fALFF and ReHo reflect different aspects of the regional spontaneous activity (An et al , 2013; Tian et al , 2016; Zhao et al , 2016), so we wondered whether the association of psychological resilience with other PFC regions, especially OFC can be seen by using the measures on neuronal activity magnitude (i.e.…”

Section: Introductioncontrasting

confidence: 54%

“…=2.01) from South China Normal University took part in the study. The current participants were completely non-overlapping with those in the study by Kong et al (2015d). All participants were right-handed and none of participants reported history of neurological or psychiatric disorders.…”

Section: Methodsmentioning

confidence: 99%

“…Subjective well-being reflects people’s cognitive (life satisfaction) and affective evaluations (hedonic balance) of their lives (Schimmack et al , 2002). A lot of research has found that psychological resilience is positively associated with hedonic balance and life satisfaction (Liu et al , 2012; Di Fabio and Palazzeschi, 2015; Kong et al , 2015d; Bajaj and Pande, 2016; Satici, 2016). In this study, we tried to investigate the neurobiological underpinnings of psychological resilience and the potential mechanism that how psychological resilience influences subjective well-being in the brain with resting-state fMRI (rs-fMRI).…”

Section: Introductionmentioning

confidence: 99%

“…Recently, Kong et al (2015d) used the ReHo measure to explore neural correlates of trait resilience, and found that higher ReHo in the ACC and insula within salience network was associated with lower trait resilience. However, as Kong et al (2015d) mentioned, this study failed to find an association of resilience with other PFC regions such as OFC, which has been demonstrated in studies on disorders related to stress, as well as studies on healthy populations (Liberzon and Sripada, 2008; Reynaud et al , 2013; Sekiguchi et al , 2015).…”

Section: Introductionmentioning

confidence: 99%

“…Importantly, some regions with the PFC related to psychological resilience (e.g. OFC and ACC) are also found to be implicated in subjective well-being (Van Reekum et al , 2007; Kong et al , 2015a,c,d, 2016a;). Notably, Kong et al (2015d) revealed that the ReHo in the ACC related to trait resilience could significantly predict the cognitive component of subjective well-being (i.e.…”

Section: Introductionmentioning

confidence: 99%

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The resilient brain: psychological resilience mediates the effect of amplitude of low-frequency fluctuations in orbitofrontal cortex on subjective well-being in young healthy adults

Kong

You

et al. 2018

Social Cognitive and Affective Neuroscience

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Psychological resilience reflects the capacity to bounce back from stress, which plays an important role in health and well-being. However, less is known about the neural substrate for psychological resilience and the underlying mechanism for how psychological resilience enhances subjective well-being in the healthy brain. To investigate these issues, we employed fractional amplitude of low-frequency fluctuations (fALFF) measured with resting-state fMRI in 100 young healthy adults. The correlation analysis found that higher psychological resilience was related to lower fALFF in the left orbitofrontal cortex (OFC), which is involved in reward-related processing and emotion regulation. Furthermore, the mediation analysis indicated that psychological resilience acted as a full mediator of the association between the fALFF in left OFC and subjective well-being indicators (i.e. life satisfaction and hedonic balance). Importantly, these results remained significant after controlling for the effect of gray matter volume and regional homogeneity in the region. Overall, the present study provides the further evidence for functional neural substrates of psychological resilience and reveals a potential mechanism that psychological resilience mediates the effect of spontaneous brain activity on subjective well-being.

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Section: Introductioncontrasting

confidence: 54%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

The resilient brain: psychological resilience mediates the effect of amplitude of low-frequency fluctuations in orbitofrontal cortex on subjective well-being in young healthy adults

Kong

You

et al. 2018

Social Cognitive and Affective Neuroscience

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Human Brain Resilience: A Call to Action

Pascual‐Leone

Bartrés‐Faz

2021

Annals of Neurology

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At present, resilience refers to a highly heterogeneous concept with ill‐defined determinants, mechanisms, and outcomes. This call for action argues for the need to define resilience as a person‐centered multidimensional metric, informed by a dynamic lifespan perspective and combining observational and interventional experimental studies to identify specific neural markers and correlated behavioral measures. The coronavirus disease 2019 (COVID‐19) pandemic highlights the urgent need of such an effort with the ultimate goal of defining a new vital sign, an individual index of resilience, as a life‐long metric with the capacity to predict an individual's risk for disability in the face of a stressor, insult, injury, or disease. ANN NEUROL 2021;90:336–349

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Prediction of life satisfaction from resting‐state functional connectome

et al. 2021

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Background: Better life satisfaction (LS) is associated with better psychological and psychiatric outcomes. To the best of our knowledge, no studies have examined prediction models for LS.Methods: Using resting-state functional magnetic resonance imaging (R-fMRI) data from the Human Connectome Project (HCP) Young Adult S1200 dataset, we examined whether LS is predictable from intrinsic functional connectivity (iFC). All the HCP data were subdivided into either discovery (n = 100) or validation (n = 766) datasets. Using R-fMRI data in the discovery dataset, we computed a matrix of iFCs between brain regions. Ridge regression, in combination with principal component analysis and 10fold cross-validation, was used to predict LS. Prediction performance was evaluated by comparing actual and predicted LS scores. The generalizability of the prediction model obtained from the discovery dataset was evaluated by applying this model to the validation dataset. Results:The model was able to successfully predict LS in the discovery dataset (r = 0.381, p < .001). The model was also able to successfully predict the degree of LS (r = 0.137, 5000-repetition permutation test p = .006) in the validation dataset, suggesting that our model is generalizable to the prediction of LS in young adults. iFCs stemming from visual, ventral attention, or limbic networks to other networks (such as the dorsal attention network and default mode network) were likely to contribute positively toward predicted LS scores. iFCs within ventral attention and limbic networks also positively contributed to predicting LS. On the other hand, iFCs stemming from the visual and cerebellar networks to other networks were likely to contribute negatively to the predicted LS scores. Conclusion:The present findings suggest that LS is predictable from the iFCs. These results are an important step toward identifying the neural basis of life satisfaction.

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Neural correlates of psychological resilience and their relation to life satisfaction in a sample of healthy young adults

Cited by 141 publications

References 85 publications

The resilient brain: psychological resilience mediates the effect of amplitude of low-frequency fluctuations in orbitofrontal cortex on subjective well-being in young healthy adults

The resilient brain: psychological resilience mediates the effect of amplitude of low-frequency fluctuations in orbitofrontal cortex on subjective well-being in young healthy adults

Human Brain Resilience: A Call to Action

Prediction of life satisfaction from resting‐state functional connectome

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