Neural correlates of context memory with real-world events

Fujii, Toshikatsu; Suzuki, Maki; Okuda, Jun; Ohtake, Hiroto; Tanji, Kazuyo; Yamaguchi, Keiichiro; Itoh, Masatoshi; Yamadori, Atsushi

doi:10.1016/j.neuroimage.2004.01.005

Cited by 49 publications

(40 citation statements)

References 55 publications

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“…This issue is discussed in the next section. The present right DL-PFC activation is also consistent with several studies investigating temporal context memory that have reported activations in this region (Cabeza, et al, 1997;Dobbins, et al, 2003;Fujii et al, 2004;Konishi, et al, 2002;Suzuki, et al, 2002). Some of these studies also found activations in left PFC (Cabeza, et al, 1997;Konishi, et al, 2002), but these activations might reflect the contributions of recollection to temporal order judgments in some conditions.…”

Section: Regions Associated With Distance Processes During Longer Timsupporting

confidence: 92%

Functional neuroimaging of autobiographical memory

Cabeza

Jacques

2007

Trends in Cognitive Sciences

627

552

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Autobiographical memory (AM) refers to memory for events from our own personal past. Functional neuroimaging studies of AM are important because they can investigate the neural correlates of processes that are difficult to study using laboratory stimuli, including: complex constructive processes, subjective qualities of memory retrieval, and remote memory. Three functional magnetic resonance imaging (fMRI) studies are presented to examine these important contributions of AM. The first study investigates the neural correlates of temporal-order memory for autobiographical events using a novel photo paradigm. Participants took photographs at many campus locations over a period of several hours, and the following day they were scanned while making temporal-order judgments to pairs of photographs from different locations. It was found that temporal-order decisions associated with recollection recruited left prefrontal (PFC) and left posterior parahippocampal cortex, whereas temporal-order decisions relying on familiarity recruited greater activity in the right PFC.The second study examines self-projection, the capacity to re-experience the personal past and to mentally infer another person's perspective. A novel camera technology was used to examine self-projection by prospectively generating dynamic visuospatial images taken from a first-person perspective. Participants were literally asked to self-project into the personal past or into the life of another person. Selfv projection of one's own past self recruited greater ventral medial PFC (mPFC), and selfprojection of another individual recruited dorsal mPFC. Activity in ventral vs. dorsal mPFC was also sensitive to the ability to relive or understand the perspective taken on each trial. Further, task-related functional connectivity analysis revealed that ventral mPFC contributed to the medial temporal lobe network linked to memory processes, whereas dorsal mPFC contributed to the frontoparietal network linked to controlled processes.The third study focuses on the neural correlates underlying age-related differences in the recall of episodically rich AMs. Age-related attenuation in the episodic richness of AM was linked to reductions in activity elicited during elaboration.Age effects on AM were more pronounced during elaboration than search, with older adults showing less sustained recruitment of the hippocampus and ventrolateral PFC for less episodically rich AMs. Further, there was an age-related reduction in the top-down modulation of the PFC on the hippocampus by episodic richness, possibly reflecting fewer controlled processes operating on the recovery of information in the hippocampus.Ultimately, the goal of all memory research is to understand how memory operates in the real-world; the present research highlights the important contribution of functional neuroimaging studies of AM in attaining this goal.vi

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Section: Regions Associated With Distance Processes During Longer Timsupporting

confidence: 92%

Functional neuroimaging of autobiographical memory

Cabeza

Jacques

2007

Trends in Cognitive Sciences

627

552

View full text Add to dashboard Cite

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“…In LTM, previous neuroimaging studies have investigated memory retrieval based on this classification [Burgess et al, 2001; Ekstrom and Bookheimer, 2007; Ekstrom et al, 2011; Fujii et al, 2004; Hayes et al, 2004; Nyberg et al, 1996]. However, the brain regions involved in attribute‐specific retrieval do not appear to correspond following long‐term retention delays [Furman et al, 2012; Magen et al, 2009] versus short‐term delays [Mohr et al, 2006; Munk et al, 2002].…”

Section: Introductionmentioning

confidence: 99%

Immediate memory for “when, where and what”: Short‐delay retrieval using dynamic naturalistic material

Kwok

Macaluso

2015

Human Brain Mapping

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We investigated the neural correlates supporting three kinds of memory judgments after very short delays using naturalistic material. In two functional magnetic resonance imaging (fMRI) experiments, subjects watched short movie clips, and after a short retention (1.5–2.5 s), made mnemonic judgments about specific aspects of the clips. In Experiment 1, subjects were presented with two scenes and required to either choose the scene that happened earlier in the clip (“scene‐chronology”), or with a correct spatial arrangement (“scene‐layout”), or that had been shown (“scene‐recognition”). To segregate activity specific to seen versus unseen stimuli, in Experiment 2 only one probe image was presented (either target or foil). Across the two experiments, we replicated three patterns underlying the three specific forms of memory judgment. The precuneus was activated during temporal‐order retrieval, the superior parietal cortex was activated bilaterally for spatial‐related configuration judgments, whereas the medial frontal cortex during scene recognition. Conjunction analyses with a previous study that used analogous retrieval tasks, but a much longer delay (>1 day), demonstrated that this dissociation pattern is independent of retention delay. We conclude that analogous brain regions mediate task‐specific retrieval across vastly different delays, consistent with the proposal of scale‐invariance in episodic memory retrieval. Hum Brain Mapp 36:2495–2513, 2015. © 2015 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.

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“…By contrast, the contribution of the frontal cortex in mnemonic context retrieval remains a matter of debate. There is functional neuroimaging and electrophysiological evidence for greater prefrontal cortex activation during the retrieval of the contextual information associated with an event compared with retrieval of the event itself [6][7][8]. Similarly, impairment in memory for source (i.e.…”

Section: Introductionmentioning

confidence: 99%

Ventrolateral and dorsomedial frontal cortex lesions impair mnemonic context retrieval

Chapados

Petrides

2015

Proc. R. Soc. B.

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The prefrontal cortex appears to contribute to the mnemonic retrieval of the context within which stimuli are experienced, but only under certain conditions that remain to be clarified. Patients with lesions to the frontal cortex, the temporal lobe and neurologically intact individuals were tested for context memory retrieval when verbal stimuli (words) had been experienced across multiple (unstable context condition) or unique (stable context condition) contexts; basic recognition memory of these words-in-contexts was also tested. Patients with lesions to the right ventrolateral prefrontal cortex (VLPFC) were impaired on context retrieval only when the words had been seen in multiple contexts, demonstrating that this prefrontal region is critical for active retrieval processing necessary to disambiguate memory items embedded across multiple contexts. Patients with lesions to the left dorsomedial prefrontal region were impaired on both context retrieval conditions, regardless of the stability of the stimulus-to-context associations. Conversely, prefrontal lesions sparing the ventrolateral and dorsomedial regions did not impair context retrieval. Only patients with temporal lobe excisions were impaired on basic recognition memory. The results demonstrate a basic contribution of the left dorsomedial frontal region to mnemonic context retrieval, with the VLPFC engaged, selectively, when contextual relations are unstable and require disambiguation.

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Neural correlates of context memory with real-world events

Cited by 49 publications

References 55 publications

Functional neuroimaging of autobiographical memory

Functional neuroimaging of autobiographical memory

Immediate memory for “when, where and what”: Short‐delay retrieval using dynamic naturalistic material

Ventrolateral and dorsomedial frontal cortex lesions impair mnemonic context retrieval

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