Neural Blockade with Neurolytic Agents

Jain, Subhash C.; Gupta, Rakesh

doi:10.1016/b978-0-7216-0334-6.50036-4

Cited by 8 publications

(3 citation statements)

References 38 publications

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“…A minimum 33% ethanol solution is required to obtain satisfactory analgesia with a neurolytic block [12]. Since the purpose of this neurolytic block was to block the sensory nerves in the abdominal wall while limiting the possible complications of the ethanol solution (ie, possibility of myonecrosis or hernia formation from the muscle laxity caused by the large area of muscle exposed to the neurolytic solution), it was decided to use a 33% ethanol solution with the neurolytic TAP block.…”

Section: Discussionmentioning

confidence: 99%

Neurolytic transversus abdominis plane block in the palliative treatment of intractable abdominal wall pain

Sakamoto

Kuber

Gwirtz

et al. 2012

Journal of Clinical Anesthesia

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Section: Discussionmentioning

confidence: 99%

Neurolytic transversus abdominis plane block in the palliative treatment of intractable abdominal wall pain

Sakamoto

Kuber

Gwirtz

et al. 2012

Journal of Clinical Anesthesia

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“…Concentrations below 50% produce no motor dysfunction, and a concentration of 100% is associated with destruction of sympathetic, sensory, and motor components of a mixed somatic nerve and also more risk of neuritis. [ 8 9 ] Therefore, we chose a concentration in between and also this percentage has been used in a previous study. [ 5 ] The absolute alcohol was diluted by adding 2% lignocaine, which decreased pain on injection and also the risk of neuritis.…”

Section: Discussionmentioning

confidence: 99%

Obturator neurolysis using 65% alcohol for adductor muscle spasticity

et al. 2012

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Spasticity is motor alteration characterized by muscle hypertonia and hyperreflexia. It is an important complication of spinal cord injury, traumatic brain injury, cerebral palsy, and multiple sclerosis. If uncorrected, fibrosis and eventually bony deformity lock the joint into a fixed contracture. Chemical neurolysis using various agents is one of the therapeutic possibilities to alleviate spasticity. We are, hereby, reporting 3 patients in whom 65% alcohol was used as neurolytic agent for the treatment of hip adductor spasticity, and the effect lasted for a variable period.

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“…Major drawbacks with the use of these agents include: necrosis of surrounding tissue, neuritis, and uncontrolled diffusion (83). Furthermore, these powerful neurolytic agents may induce sequelae in the axonal membrane, which might explain cases of painful paresthesia observed several months following a neurolytic block: this is known to be deafferentation pain sequelae [ 97 ]. These techniques are also associated with neuroma formation [ 98 ].…”

Section: Interventional Managementmentioning

confidence: 99%

Facet joint syndrome: from diagnosis to interventional management

et al. 2018

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Low back pain (LBP) is the most common pain syndrome, and is an enormous burden and cost generator for society. Lumbar facet joints (FJ) constitute a common source of pain, accounting for 15–45% of LBP. Facet joint degenerative osteoarthritis is the most frequent form of facet joint pain. History and physical examination may suggest but not confirm facet joint syndrome. Although imaging (radiographs, MRI, CT, SPECT) for back pain syndrome is very commonly performed, there are no effective correlations between clinical symptoms and degenerative spinal changes. Diagnostic positive facet joint block can indicate facet joints as the source of chronic spinal pain. These patients may benefit from specific interventions to eliminate facet joint pain such as neurolysis, by radiofrequency or cryoablation. The purpose of this review is to describe the anatomy, epidemiology, clinical presentation, and radiologic findings of facet joint syndrome. Specific interventional facet joint management will also be described in detail.Teaching points • Lumbar facet joints constitute a common source of pain accounting of 15–45%. • Facet arthrosis is the most frequent form of facet pathology. • There are no effective correlations between clinical symptoms, physical examination and degenerative spinal changes. • Diagnostic positive facet joint block can indicate facet joints as the source of pain. • After selection processing, patients may benefit from facet joint neurolysis, notably by radiofrequency or cryoablation.

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Neural Blockade with Neurolytic Agents

Cited by 8 publications

References 38 publications

Neurolytic transversus abdominis plane block in the palliative treatment of intractable abdominal wall pain

Neurolytic transversus abdominis plane block in the palliative treatment of intractable abdominal wall pain

Obturator neurolysis using 65% alcohol for adductor muscle spasticity

Facet joint syndrome: from diagnosis to interventional management

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