Neural Basis of tDCS Effects on Auditory Verbal Hallucinations in Schizophrenia

Nawani, Hema; Kalmady, Sunil V.; Bose, Anushree; Shivakumar, Venkataram; Rakesh, Gopalkumar; Subramaniam, Aditi; Narayanaswamy, Janardhanan C.; Venkatasubramanian, Ganesan

doi:10.1097/yct.0b013e3182a35492

Cited by 30 publications

(13 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This is why tDCS sessions were maintained for 3 years (Andrade, 2013). A more recent case study by Nawani et al (2014) replicated these findings and supports the use of tDCS in the treatment of auditory hallucinations. Another case study, with a pregnant patient (a case where tDCS might be particularly appropriate as many antipsychotic medications are considered teratogenic while there are no significant contraindications for tDCS), has observed a significant decrease in auditory hallucinations after 5 days of auditory cortex tDCS (Shenoy et al, 2015).…”

Section: Auditorysupporting

confidence: 64%

Transcranial direct current stimulation as a tool in the study of sensory-perceptual processing

Costa

Lapenta

Boggio

et al. 2015

Atten Percept Psychophys

View full text Add to dashboard Cite

Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulatory technique with increasing popularity in the fields of basic research and rehabilitation. It is an affordable and safe procedure that is beginning to be used in the clinic, and is a tool with potential to contribute to the understanding of neural mechanisms in the fields of psychology, neuroscience, and medical research. This review presents examples of investigations in the fields of perception, basic sensory processes, and sensory rehabilitation that employed tDCS. We highlight some of the most relevant efforts in this area and discuss possible limitations and gaps in contemporary tDCS research. Topics include the five senses, pain, and multimodal integration. The present work aims to present the state of the art of this field of research and to inspire future investigations of perception using tDCS.

show abstract

Section: Auditorysupporting

confidence: 64%

Transcranial direct current stimulation as a tool in the study of sensory-perceptual processing

Costa

Lapenta

Boggio

et al. 2015

Atten Percept Psychophys

View full text Add to dashboard Cite

show abstract

“…Nawani et al [41]. and Shivakumar et al [42] used similar treatment protocols (5 days of tDCS, two sessions per day, with cathode over the left temporoparietal junction and the anode over the left DLPFC, describing improvement in auditory hallucinations).…”

Section: Case Reportsmentioning

confidence: 96%

Understanding tDCS effects in schizophrenia: a systematic review of clinical data and an integrated computation modeling analysis

Brunoni

Shiozawa²,

Truong

et al. 2014

Expert Review of Medical Devices

View full text Add to dashboard Cite

Although recent clinical studies using transcranial direct current stimulation (tDCS) for schizophrenia showed encouraging results, several tDCS montages were employed and their current flow pattern has not been investigated. We performed a systematic review to identify clinical tDCS studies in schizophrenia. We then applied computer head modeling analysis for prediction of current flow. Out of 41 references, we identified 12 relevant studies. The most employed montage was anode and cathode over the left dorsolateral prefrontal and temporoparietal cortex, respectively. Computational model analysis predicted activation and under-activation under the anode and the cathode, respectively, occurring in areas respectively associated with negative and positive symptoms. We also identified tDCS-induced electrical currents in cortical areas between the electrodes (frontoparietal network) and, to a lesser extent, in deeper structures involved in schizophrenia pathophysiology. Mechanisms of tDCS effects in schizophrenia and the usefulness of computer modeling techniques for planning tDCS trials in schizophrenia are discussed.

show abstract

“…Hierbei konnte die Wirksamkeit der tDCS für relevante psychopathologische Symptome der Schizophrenie gezeigt werden, z. B. akustische Halluzinationen (11)(12)(13)(14)(15)(16)(17), optische Halluzinationen (18), katatone Schizophrenie (19) und Negativsyndrom (20).…”

Section: Discussionunclassified

Bifrontale transkranielle Gleichstromstimulation zur Behandlung der Schizophrenie

Palm¹,

Hasan²,

Dehning³

et al. 2014

Nervenheilkunde

View full text Add to dashboard Cite

Zusammenfassung Gegenstand und Ziel: Die transkranielle Gleichstromstimulation (transcranial direct current stimulation, tDCS) wird als neues nicht invasives Hirnstimulationsverfahren für die Behandlung neurologischer und psychiatrischer Erkrankungen untersucht. Mittlerweile gibt es Fallberichte und eine randomisierte, kontrollierte Pilotstudie zur Behandlung akustischer Halluzinationen sowie der Negativsymptomatik bei Schizophrenie. Fallbericht: Im vorliegenden Fallbericht wurde ein Patient mit therapieresistenter Symptomatik bei paranoider Schizophrenie drei Wochen lang mit anodaler tDCS über dem linken dorsolateralen und kathodaler tDCS über dem rechten dorsolateralen Kortex behandelt. Ergebnisse: Es zeigte sich eine Verbesserung von Affektivität und Kognition, die Positivsymptome blieben jedoch nahezu unverändert. Klinische Relevanz: Die bifrontale tDCS stellt eine nebenwirkungsarme neue Behandlungsform dar und sollte in der Anwendung bei Erkrankungen aus dem schizophrenen Formenkreis weiter untersucht werden.

show abstract

Neural Basis of tDCS Effects on Auditory Verbal Hallucinations in Schizophrenia

Cited by 30 publications

References 0 publications

Transcranial direct current stimulation as a tool in the study of sensory-perceptual processing

Transcranial direct current stimulation as a tool in the study of sensory-perceptual processing

Understanding tDCS effects in schizophrenia: a systematic review of clinical data and an integrated computation modeling analysis

Bifrontale transkranielle Gleichstromstimulation zur Behandlung der Schizophrenie

Contact Info

Product

Resources

About